1358418-57-1

Basic information

• Product Name: N-cyanomethyl-N,N-dimethyl-N-(α-methoxycarbonylbenzyl)ammonium trifluoromethanesulfonate
• Synonyms: N-cyanomethyl-N,N-dimethyl-N-(α-methoxycarbonylbenzyl)ammonium trifluoromethanesulfonate
• CAS NO: 1358418-57-1
• Molecular Weight: 382.361
• Mol File: 1358418-57-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-cyanomethyl-N,N-dimethyl-N-(α-methoxycarbonylbenzyl)ammonium trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyanomethyl-N,N-dimethyl-N-(α-methoxycarbonylbenzyl)ammonium trifluoromethanesulfonate(1358418-57-1)
• EPA Substance Registry System: N-cyanomethyl-N,N-dimethyl-N-(α-methoxycarbonylbenzyl)ammonium trifluoromethanesulfonate(1358418-57-1)

Safety Data

• Hazardous Substances Data: 1358418-57-1(Hazardous Substances Data)

Upstream product

• 107635-11-0 methyl α-(N-methylamino)phenylacetate 
• 1358418-45-7 methyl α-(N-cyanomethyl-N-methylamino)phenylacetate 
• 333-27-7 methyl trifluoromethanesulfonate 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 

Downstream Products

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 5894-79-1 methyl 2-formyl-2-phenylacetate 
• 1358418-47-9 2-(methoxycarbonylmethyl)-α-(dimethylamino)phenylacetonitrile 
• 127218-69-3 3-cyano-3-dimethylamino-2-phenylpropionic acid methyl ester 
• 63969-83-5 2-formylphenylacetic acid methyl ester 

Relevant articles and documents

Sigmatropic rearrangement of ammonium ylideskey step in the synthesis of methyl 2-formylphenyl acetate

N-Cyanomethyl-N,N-dimethyl-N-(-methoxycarbonyl)benzylammonium salts 5 were synthesized and treated with different base/solvent systems, giving the products of sigmatropic rearrangements [2,3] 7 and [1,2] 8. In reactions carried out in liquid ammonia, [2,3] rearrangement definitively prevailed. Pure 7(or mixture of 7 and 8) were deprotected to afford methyl 2-formylphenyl acetate (9) in good yield.