1358946-07-2

Basic information

• Product Name: C₁₉H₂₂FN₃
• CAS NO: 1358946-07-2
• Molecular Weight: 311.402
• Mol File: 1358946-07-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₂FN₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₂FN₃(1358946-07-2)
• EPA Substance Registry System: C₁₉H₂₂FN₃(1358946-07-2)

Safety Data

• Hazardous Substances Data: 1358946-07-2(Hazardous Substances Data)

Upstream product

• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 51-35-4 4R-4-hydroxyproline 
• 72180-14-4 N-<(phenylmethoxy)carbonyl>-4(S)-fluoro-(S)-proline methyl ester 
• 64187-48-0 methyl (2S,4R)-1-benzyloxycarbonyl-4-hydroxypyrrolidine-2-carboxylate 
• 1358943-62-0 C₁₃H₁₄FNO₃ 

Relevant articles and documents

Conformationally stabilized catalysts by fluorine insertion: Tool for enantioselectivity improvement

F rigid cats: The power of conformationally stabilized catalysts is demonstrated. By taking appropriate advantage of fluorine insertion (see scheme), purely conformational catalyst design led to a notable improvement in enantioselectivities from around 70% to 91-98.5% ee. The other advantage of this approach is the better understanding of the origin of the stereoselectivity in the given catalytic system. Copyright