136-99-2

Basic information

• Product Name: 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol
• Synonyms: 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol;LAURYL HYDROXYETHYL IMIDAZOLINE;1H-Imidazole-1-ethanol, 4,5-dihydro-2-undecyl-;1-Hydroxyethyl-2-undecylimidazoline;4,5-dihydro-2-undecyl-1h-imidazole-1-ethano;LURYLIMIDAZOLINE;1-(2-Hydroxyethyl)-2-undecylimadazoline;1-(2-Hydroxyethyl)-2-undecyl-2-imidazoline
• CAS NO: 136-99-2
• Molecular Formula: C₁₆H₃₂N₂O
• Molecular Weight: 268.43808
• EINECS: 205-271-0
• Mol File: 136-99-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 57 °C
• Boiling Point: 411.5 °C at 760 mmHg
• Flash Point: 202.7 °C
• Appearance: /
• Density: 0.98 g/cm³
• Vapor Pressure: 1.72E-08mmHg at 25°C
• Refractive Index: 1.506
• PKA: 15.07±0.10(Predicted)
• Water Solubility: 33.9mg/L at 20℃
• CAS DataBase Reference: 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol(136-99-2)
• EPA Substance Registry System: 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol(136-99-2)

Safety Data

• RIDADR: 3267
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 136-99-2(Hazardous Substances Data)

Usage

Flammability and Explosibility

Nonflammable

InChI:InChI=1/C16H32N2O/c1-2-3-4-5-6-7-8-9-10-11-16-17-12-13-18(16)14-15-19/h19H,2-15H2,1H3

Upstream product

• 143-07-7 lauric acid 
• 111-41-1 2-(2-Aminoethylamino)ethanol 
• 106-33-2 ethyl laurate 
• 111-82-0 methyl n-dodecanoate 

Relevant articles and documents

Synthesis of Long Chain 2-Alkyl-1-(2-hydroxyethyl)-2-imidazolines under Microwave in Solvent-Free Conditions

An efficient method for the synthesis of long chain 2-alkyl-1-(2-hydroxyethyl)-2-imidazolines, and their amide precursors, by condensing aminoethylethanolamine and several fatty acids under non-solvent microwave irradiation using CaO as support, is described. Products were obtained in good yields and high purity in a few minutes, in both multimode microwave and monomode microwave oven. Evidences of non-thermal microwave effects are given.

Imidazoline quaternary ammonium salt compound and preparation method therefor

Provided are an imidazoline quaternary ammonium salt compound and a preparation method therefor. Lauric acid and hydroxyethyl ethylenediamine are employed as raw materials, a dehydration reaction is carried out, imidazoline intermediates are synthesized, and then after quaternization, an imidazoline quaternary ammonium salt compound is obtained, wherein a quaternized reagent is sulfamic acid. Sulfamic acid is employed as a quaternized reagent, thus the quaternization reaction is carried out easily, and the product water solubility is raised. The imidazoline quaternary ammonium salt employs sulfamic acid as a quaternized reagent, and sulfamic acid has low toxicity, and is cheap and easily available. An imidazoline sulfuric ester salt is obtained through the method, and the imidazoline sulfuric ester salt is an amphoteric substance. The product contains -SO3 hydrophilic groups, the water solubility is good, the inhibition efficiency is high, water solubility requirements of imidazoline products can be met, and popularization in the industrial process is worthy. The synthetic technology is simple, the production processes are environmentally friendly, and the purposes of lowering the corrosion inhibitor cost and raising the operation safety are achieved.

Compositions and method comprising heterocyclic compounds containing two heteroatoms as membrane penetration enhancers

A method and compositions for enhancing absorption of topically administered physiologically active agents through the skin and mucous membranes of humans and animals in a transdermal device or formulation for local or systemic use, comprising a therapeutically effective amount of a pharmaceutically active agent and a non-toxic, effective amount of penetration enhancing agent of the formula I: STR1 wherein R is a saturated or unsaturated, straight or branched, cyclic or acyclic hydrocarbon group with from 1 to 19 carbon atoms, alkoxyalkyl, haloalkyl, specifically trifluoromethyl, alkoxy, amino, alkylamino and acylamino; R' and R" are hydrogen, alkyl, trifluoromethyl, alkoxyalkyl, aminoalkyl, alkyl- and acylaminoalkyl, carboxy, carbalkoxy, hydroxyalkyl or lower alkyl ester thereof; X is O or NR1 wherein R1 is hydrogen, alkyl, alkenyl, alkoxyalkyl, carbalkoxyalkyl, aminoalkyl, alkyl- and acylaminoalkyl, hydroxyalkyl or hydroxyalkyloxyalkyl and lower alkyl ester thereof; and n is 2 or 3 are disclosed.