136015-39-9 Usage
Description
(S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone, a chiral oxazolidinone derivative with the chemical formula C11H13NO3, is a compound that features a benzyl moiety and a hydroxymethyl group. It has been explored for its potential as a chiral auxiliary in asymmetric synthesis and as a building block in the creation of various pharmaceutical compounds. Its unique structure and properties render it a valuable intermediate in organic synthesis, particularly for the synthesis of chiral compounds. Furthermore, the oxazolidinone ring system has been investigated for its potential as a pharmacophore in drug discovery and development.
Uses
Used in Pharmaceutical Industry:
(S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone is used as a chiral auxiliary for enhancing the selectivity and yield in asymmetric synthesis, which is crucial for producing enantiomerically pure compounds that are often required for pharmaceutical applications.
Used in Organic Synthesis:
(S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone is used as a building block in the preparation of various pharmaceutical compounds, contributing to the development of new drugs with improved efficacy and selectivity.
Used in Drug Discovery and Development:
(S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone is used as a potential pharmacophore in drug discovery and development, due to its oxazolidinone ring system, which may play a role in the interaction with biological targets and contribute to the compound's therapeutic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 136015-39-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,0,1 and 5 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 136015-39:
(8*1)+(7*3)+(6*6)+(5*0)+(4*1)+(3*5)+(2*3)+(1*9)=99
99 % 10 = 9
So 136015-39-9 is a valid CAS Registry Number.
136015-39-9Relevant articles and documents
Heterolignans: Stereoselective synthesis of an 11-amino analog of azaelliptitoxin
Routier, Julie,Calancea, Mihaela,David, Marion,Vallee, Yannick,Denis, Jean-Noel
supporting information; experimental part, p. 5687 - 5691 (2009/05/31)
The 11-amino-azaelliptitoxin analog (11R,11aS,5R)-15 has been prepared stereoselectively in eight steps and 24% over-all yield from commercially available (S)-glycidol (7) via the original enantiopure chiral α-amino aldehyde 9, used as chiral precursor fo
Synthesis of Optically Pure 4-Hydroxymethyloxazolidinone as Chiral Serinol Synthon from Glycidol
Katsumura, Shigeo,Kondo, Akihiro,Han, Quingjun
, p. 1245 - 1248 (2007/10/02)
Optically pure 3-benzyl-4-hydroxymethyl-2-oxazolidinone and 4-benzoyloxymethyl-2-oxazolidinone as chiral serinol synthons were synthesized from optically active glycidol by intramolecular cyclization via 2,3-epoxycarbamates with strict SN2 beha