1361190-38-6

Basic information

• Product Name: 4-[4-(3-{1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-cyclobutyl}-[1,2,4]oxadiazol-5-yl)-thiazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-[4-(3-{1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-cyclobutyl}-[1,2,4]oxadiazol-5-yl)-thiazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 1361190-38-6
• Molecular Weight: 559.692
• Mol File: 1361190-38-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[4-(3-{1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-cyclobutyl}-[1,2,4]oxadiazol-5-yl)-thiazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-(3-{1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-cyclobutyl}-[1,2,4]oxadiazol-5-yl)-thiazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester(1361190-38-6)
• EPA Substance Registry System: 4-[4-(3-{1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-cyclobutyl}-[1,2,4]oxadiazol-5-yl)-thiazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester(1361190-38-6)

Safety Data

• Hazardous Substances Data: 1361190-38-6(Hazardous Substances Data)

Upstream product

• 365413-00-9 4-(4-carboxy-thiazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1361189-49-2 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-hydroxycyclobutanecarboxamidine 
• 365413-31-6 ethyl 2-(1-(tert-butoxy carbonyl )piperidin-4-yl)thiazole-4-carboxylate 
• 214834-18-1 tert-butyl 4-carbamothioylpiperidine-1-carboxylate 

Downstream Products

• 1361188-98-8 5-(4-{1-[5-(2-piperidin-4-yl-thiazol-4-yl)-[1,2,4]oxadiazol-3-yl]-cyclobutyl}-phenyl)pyrimidin-2-ylamine 

Relevant articles and documents

OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION

The present invention relates to compound of formula (I) and pharmaceutically acceptable salt thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.