136315-71-4

Basic information

• Product Name: Boc-trans-2-aMinocyclopentane carboxylic acid
• Synonyms: Boc-trans-2-aMinocyclopentane carboxylic acid;TRANS(+/-) 2-(BOC-AMINO)CYCLOPENTANE CARBOXYLIC ACID
• CAS NO: 136315-71-4
• Molecular Formula: C₁₁H₁₉NO₄
• Molecular Weight: 229.27286
• Mol File: 136315-71-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 137-138 °C
• Boiling Point: 382.5±31.0 °C(Predicted)
• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.53±0.40(Predicted)
• CAS DataBase Reference: Boc-trans-2-aMinocyclopentane carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-trans-2-aMinocyclopentane carboxylic acid(136315-71-4)
• EPA Substance Registry System: Boc-trans-2-aMinocyclopentane carboxylic acid(136315-71-4)

Safety Data

• Hazardous Substances Data: 136315-71-4(Hazardous Substances Data)

Usage

General Description

Boc-trans-2-amino cyclopentane carboxylic acid is a chemical compound that consists of a cyclopentane ring with an amino group and a carboxylic acid group attached to it. The abbreviation "Boc" stands for tert-butoxycarbonyl, which is a protecting group used in organic synthesis to protect the amino group from unwanted reactions. Boc-trans-2-aMinocyclopentane carboxylic acid is an important intermediate in the synthesis of various pharmaceuticals and biologically active molecules. It is commonly used in peptide synthesis and as a building block in organic chemistry. Its unique structure and reactivity make it a versatile and valuable compound in the field of organic chemistry and drug discovery.

Downstream Products

• 494209-39-1 C₆H₁₂N₂O*(x)ClH 
• 137894-55-4 N-(benzyloxycarbonyl)-β-benzyl-L-aspartyl-trans-(1R,2R)-2-aminocyclopentanecarboxylic acid methyl ester 
• 136315-66-7 N-(benzyloxycarbonyl)-β-benzyl-L-aspartyl-trans-(1S,2S)-2-aminocyclopentanecarboxylic acid methyl ester 
• 136315-75-8 -(R)-(+)-α-methylbenzylamine 
• 136237-71-3 (trans-(1S,2S)-2-aminocyclopentanecarbonyl)-(R)-(+)-α-methylbenzylamine 
• 136315-76-9 (trans-(1R,2R)-2-aminocyclopentanecarbonyl)-(R)-(+)-α-methylbenzylamine 
• 64191-13-5 (+)-(1S,2S)-2-aminocyclopentane-1-carboxylic acid 
• 136315-77-0 trans-(1R,2R)-2-aminocyclopentanecarboxylic acid 
• 57043-01-3 (+/-)-trans-2-amino-cyclopentane carboxylic acid 

Relevant articles and documents

Radical cyclization in heterocycle synthesis. Part 13: Sulfanyl radical addition-cyclization of oxime ethers and hydrazones connected with alkenes for synthesis of cyclic β-amino acids

A combination of sulfanyl radical addition-cyclization of the oxime ethers and hydrazones connected with alkenes and subsequent conversion of a phenylsulfanylmethyl group to a carboxyl group provides a novel method for the construction of the cyclic β-amino acids. Upon treatment with thiophenol in the presence of AIBN, the oxime ethers and hydrazones smoothly underwent sulfanyl radical addition-cyclization to give the 2-(phenylsulfanylmethyl)cycloalkylamine. This method was successfully applied to the practical synthesis of 2-aminocyclopentanecarboxylic acid and 4-amino-3-pyrrolidinecarboxylic acid.