136465-80-0

Basic information

• Product Name: 2(S)-[2-phenyl-1(S)-phthalimidoethyl]oxirane
• Synonyms: 2(S)-[2-phenyl-1(S)-phthalimidoethyl]oxirane
• CAS NO: 136465-80-0
• Molecular Weight: 293.322
• Mol File: 136465-80-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2(S)-[2-phenyl-1(S)-phthalimidoethyl]oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: 2(S)-[2-phenyl-1(S)-phthalimidoethyl]oxirane(136465-80-0)
• EPA Substance Registry System: 2(S)-[2-phenyl-1(S)-phthalimidoethyl]oxirane(136465-80-0)

Safety Data

• Hazardous Substances Data: 136465-80-0(Hazardous Substances Data)

Upstream product

• 136465-83-3 2(R)-(Methanesulfonyloxy)-4-phenyl-3(S)-phthalimido-1-butanol 
• 161525-69-5 (2S,3S)-4-phenyl-3-phthalimidobutane-1,2-diol 
• 78571-81-0 (R,R)-3-(phenylmethyl)oxiranemethanol 
• 116949-67-8 (2S,3S)-2-azido-1-phenyl-butane-3,4-diol 
• 147915-02-4 (2S,3S)-3-amino-4-phenylbutane-1,2-diol 
• 1055033-80-1 Methanesulfonic acid (1R,2S)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-1-(tetrahydro-pyran-2-yloxymethyl)-propyl ester 
• 1054798-68-3 2-[(1S,2R)-1-Benzyl-2-hydroxy-3-(tetrahydro-pyran-2-yloxy)-propyl]-isoindole-1,3-dione 
• 1026632-96-1 2-[(S)-1-Benzyl-2-oxo-3-(tetrahydro-pyran-2-yloxy)-propyl]-isoindole-1,3-dione 
• 32150-91-7 phthaloyl-L-phenylalanyl chloride 
• 5123-55-7 Nα-phthaloyl-L-phenylalanine 
• 136465-82-2 1-Hydroxy-4-phenyl-3(S)-phthalimido-2-butanone 
• 63-91-2 L-phenylalanine 
• 85-44-9 phthalic anhydride 

Downstream Products

• 127779-20-8 Saquinavir 
• 136522-17-3 cis-N-butyldecahydro-2-<2(R)-hydroxy-4-phenyl-3(S)-aminobutyl>-(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 137431-06-2 2-[3(S)-[(L-asparaginyl)-amino]-2(R)-hydroxy-4-phenylbutyl]-N-tert-butyl-decahydro(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 136522-18-4 2-<3(S)-<amino>-2(R)-hydroxy-4-phenylbutyl>-N-tert-butyldecahydro-(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 688349-19-1 2-[(S)-1-((3R,4aR,8aS)-7-Benzyl-1-oxo-6-trimethylsilanyloxy-3,4,4a,5,8,8a-hexahydro-1H-isochromen-3-yl)-2-phenyl-ethyl]-isoindole-1,3-dione 
• 688349-21-5 2-[(S)-1-((3R,4aS,5R,7aS)-5-Benzenesulfonyl-6-methylene-1-oxo-octahydro-cyclopenta[c]pyran-3-yl)-2-phenyl-ethyl]-isoindole-1,3-dione 
• 688349-14-6 (5R,6S)-6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-5-hydroxy-7-phenyl-hept-2-ynoic acid methyl ester 
• 688349-11-3 2-((1S,2R)-1-Benzyl-2-hydroxy-pent-4-ynyl)-isoindole-1,3-dione 
• 688349-15-7 2-[(S)-1-((R)-6-Oxo-3,6-dihydro-2H-pyran-2-yl)-2-phenyl-ethyl]-isoindole-1,3-dione 
• 207281-59-2 (4R,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-6-phenyl-hexanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 136465-78-6 N-tert-Butyldecahydro-2-(2(R)-hydroxy-4-phenyl-3(S)phthalimidobutyl)-(4aS,8aS)-isoquinoline-3(S)-carboxamide 

Relevant articles and documents

A General, Catalytic, and Enantioselective Synthesis of (S)-γ-[(S)-1-Aminoalkyl]-γ-lactones

A catalytic asymmetric synthesis of N-phthaloyl (S)-γ-[(S)-1-aminoalkyl]-γ-lactones, widely used intermediates in the preparation of hydroxyethylene dipeptide isosteres, is described. The highly enantiopure epoxy alcohols arising from the Sharpless epoxid

Alcohols

Novel alcohols of the formula STR1 wherein Ra is azido or phthalimido, R4 is alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, R7 and R8 together are a trimethylene or tetramethylene group which is optionally substituted by hydroxy, alkoxycarbonylamino or acylamino or in which one --CH2 -- group is replaced by --NH--, --N(alkoxycarbonyl)-, --N(acyl)- or --S-- or which carries a fused cycloalkane, aromatic or heteroaromatic ring, and R9 is alkoxycarbonyl, monoalkylcarbamoyl, monoaralkylcarbamoyl, monoarylcarbamoyl or a group of the formula STR2 in which R10 and R11 each is alkyl, are described along with a process for their manufacture. These alcohols are useful as intermediates, for example in the manufacture of amino acid derivatives having antiviral activity.