136812-19-6

Basic information

• Product Name: 2-CHLORO-3-QUINOLINECARBONYL CHLORIDE
• Synonyms: 2-CHLORO-3-QUINOLINECARBONYL CHLORIDE;2-Chloro-3-quinolinecarbonyl chloride , Tech.
• CAS NO: 136812-19-6
• Molecular Formula: C₁₀H₅Cl₂NO
• Molecular Weight: 226.06
• Mol File: 136812-19-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 347°C at 760 mmHg
• Flash Point: 163.6°C
• Appearance: /
• Density: 1.457g/cm³
• Vapor Pressure: 5.56E-05mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: 2-CHLORO-3-QUINOLINECARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-QUINOLINECARBONYL CHLORIDE(136812-19-6)
• EPA Substance Registry System: 2-CHLORO-3-QUINOLINECARBONYL CHLORIDE(136812-19-6)

Safety Data

• Hazardous Substances Data: 136812-19-6(Hazardous Substances Data)

Usage

General Description

2-Chloro-3-quinolinecarbonyl chloride is a chemical compound with the molecular formula C10H6Cl2NO2. It is a chlorinated quinoline derivative that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2-CHLORO-3-QUINOLINECARBONYL CHLORIDE is a reactive acylating agent and is commonly used in organic synthesis as a building block for the preparation of various molecules. It is a powerful lachrymator and should be handled with extreme caution due to its corrosive nature and potential for causing severe eye and skin irritation. 2-Chloro-3-quinolinecarbonyl chloride is commonly used in pharmaceutical and agrochemical research and development for its ability to modify and enhance the properties of various compounds.

InChI:InChI=1/C10H5Cl2NO/c11-9-7(10(12)14)5-6-3-1-2-4-8(6)13-9/h1-5H

Upstream product

• 73776-25-7 2-chloro-3-quinolinecarboxylic acid 
• 73568-25-9 2-chloro-3-quinoline carboxaldehyde 
• 2003-79-4 2-oxo-1,2-dihydro-quinoline-3-carboxylic acid 
• 612-62-4 2-Chloroquinoline 
• 36926-82-6 2-oxo-1,2-dihydroquinoline-3-carbonitrile 

Downstream Products

• 16498-86-5 2-chloroquinoline-3-carboxylic acid ethyl ester 
• 832096-89-6 N-[(1S)-1-(2-iodophenyl)ethyl]-N-isopropyl-2-chloroquinoline-3-carboxamide 
• 638169-42-3 2-(2-acetylphenyl)quinoline-3-carboxylic acid ethyl ester 
• 929569-12-0 1-phenylpyrazolo[4',3':5,6]pyrano[2,3-b]quinolin-4(1H)-one 
• 929569-11-9 3-methyl-1-phenylpyrazolo[4',3':5,6]pyrano[2,3-b]quinolin-4(1H)-one 
• 1204601-62-6 1-(2-chloroquinolin-3-yl)-3-phenylprop-2-yn-1-one 
• 1621108-31-3 5-(2-(2-chloro-4-fluorophenoxy)quinoline-3-carboxamido)picolinic acid 
• 1621108-34-6 4-(2-(2,4-difluorophenoxy)quinoline-3-carboxamido)benzoic acid 
• 1621109-02-1 C₂₄H₁₆F₂N₂O₄ 
• 1621109-01-0 methyl 4-(2-chloroquinoline-3-carboxamido)benzoate 

Relevant articles and documents

QUINOLINE AND QUINAZOLINE AMIDES AS MODULATORS OF SODIUM CHANNELS

The invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels: formula (I). The invention also provides pharmaceutically acceptable compositions comprising the compounds of the inve

An efficient approach to heterocyclic analogues of xanthone: A short synthesis of all possible pyrido[5,6]pyrano[2,3-c]pyrazol-4(1H)-ones

An efficient and generally applicable synthesis of various [5,6]pyrano[2,3-c]pyrazol-4(1H)-ones by the reaction of either 1-substituted or 1,3-disubstituted 2-pyrazolin-5-ones with different o-halopyridinecarbonyl chlorides or with 3-chloroquinoline-2-car

Novel Extension of Meyers' Methodology: Stereoselective Construction of Axially Chiral 7,5-Fused Bicyclic Lactams

A novel extension of Meyer's lactamization is reported for the preparation of seven-membered ring lactams 1a-d incorporating a biaryl unit. The required keto-esters 2a-c were readily accessible via the Suzuki coupling reaction. A borylation-Suzuki couplin