1372687-86-9Relevant articles and documents
Asymmetric michael addition of substituted rhodanines to α,β-unsaturated ketones catalyzed by bulky primary amines
Yu, Feng,Hu, Haoxiang,Gu, Xiaodong,Ye, Jinxing
, p. 2038 - 2041 (2012/07/28)
A bulky group was introduced by design into a diamine catalyst, and a series of robust and tunable bulky chiral primary amine catalysts were developed and successfully applied in the direct conjugate addition of substituted rhodanines to α,β-unsaturated ketones. High yields (up to 99%) and excellent diastereoselectivities (up to 99:1 dr) and enantioselectivities (up to 98% ee) were observed.