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1374832-51-5

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1374832-51-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1374832-51-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,4,8,3 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1374832-51:
(9*1)+(8*3)+(7*7)+(6*4)+(5*8)+(4*3)+(3*2)+(2*5)+(1*1)=175
175 % 10 = 5
So 1374832-51-5 is a valid CAS Registry Number.

1374832-51-5Downstream Products

1374832-51-5Relevant articles and documents

In vitro inhibition effect and structure-activity relationships of some saccharin derivatives on erythrocyte carbonic anhydrase i and II

Sonmez, Fatih,Bilen, Cigdem,Sumersan, Sinem,Gencer, Nahit,Isik, Semra,Arslan, Oktay,Kucukislamoglu, Mustafa

, p. 118 - 123 (2014/03/21)

In this study, in vitro inhibitory effects of some saccharin derivatives on purified carbonic anhydrase I and II were investigated using CO2 as a substrate. The results showed that all compounds inhibited the hCA I and hCA II enzyme activities. Among the compounds, 6-(p-tolylthiourenyl) saccharin (6m) was found to be the most active one for hCA I activity (IC50 = 13.67 μM) and 6-(m-methoxyphenylurenyl) saccharin (6b) was found to be the most active one for hCA II activity (IC50 = 6.54 μM). Structure-activity relationships (SARs) study showed that, generally, thiourea derivatives (6l - v) inhibited more hCA I and hCA II than urea derivatives (6a-k). All compounds (excluding 6c and 6r) have higher inhibitory activity on hCA II than on hCA I.

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