137513-39-4

Basic information

• Product Name: Acetic acid (E)-4-hydroxy-4-methyl-6-phenyl-hex-2-enyl ester
• Synonyms: Acetic acid (E)-4-hydroxy-4-methyl-6-phenyl-hex-2-enyl ester
• CAS NO: 137513-39-4
• Molecular Weight: 248.322
• Mol File: 137513-39-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetic acid (E)-4-hydroxy-4-methyl-6-phenyl-hex-2-enyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (E)-4-hydroxy-4-methyl-6-phenyl-hex-2-enyl ester(137513-39-4)
• EPA Substance Registry System: Acetic acid (E)-4-hydroxy-4-methyl-6-phenyl-hex-2-enyl ester(137513-39-4)

Safety Data

• Hazardous Substances Data: 137513-39-4(Hazardous Substances Data)

Upstream product

• 627-09-8 Propargyl acetate 
• 2550-26-7 4-Phenyl-2-butanone 
• 25260-60-0 cis-1,4-bis(acetyloxy)but-2-ene 
• 55066-45-0 3-methyl-5-phenylpent-1-en-3-ol 

Relevant articles and documents

Stereoselective Dynamic Cyclization of Allylic Azides: Synthesis of Tetralins, Chromanes, and Tetrahydroquinolines

This report describes the stereoselective synthesis of 3-azido-tetralins, -chromanes, and -tetrahydroquinolines via a tandem allylic azide rearrangement/Friedel-Crafts alkylation. Exposure of allylic azides with a pendant trichloroacetimidate to catalytic quantities of AgSbF6 proved optimal for this transformation. This cascade successfully differentiates the equilibrating azide isomers, providing products in excellent yield and selectivity (>25 examples, up to 94% yield and >25:1 dr). In many cases, the reactive isomer is only a trace fraction of the equilibrium mixture, keenly illustrating the dynamic nature of these systems. We demonstrate the utility of this process via a synthesis of hasubanan.