1380048-91-8

Basic information

• Product Name: (S)-2-{(R)-hydroxy[4'-methyl-1,1'-biphenyl-4-yl]methyl}cyclopentanone
• Synonyms: (S)-2-{(R)-hydroxy[4'-methyl-1,1'-biphenyl-4-yl]methyl}cyclopentanone
• CAS NO: 1380048-91-8
• Molecular Weight: 280.367
• Mol File: 1380048-91-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-{(R)-hydroxy[4'-methyl-1,1'-biphenyl-4-yl]methyl}cyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-{(R)-hydroxy[4'-methyl-1,1'-biphenyl-4-yl]methyl}cyclopentanone(1380048-91-8)
• EPA Substance Registry System: (S)-2-{(R)-hydroxy[4'-methyl-1,1'-biphenyl-4-yl]methyl}cyclopentanone(1380048-91-8)

Safety Data

• Hazardous Substances Data: 1380048-91-8(Hazardous Substances Data)

Upstream product

• 36393-42-7 4-(4-methylphenyl)benzaldehyde 
• 120-92-3 cyclopentanone 
• 624-31-7 4-tolyl iodide 
• 87199-17-5 4-formylphenylboronic acid, 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

Chiral Proline-Decorated Bifunctional Pd?NH2-UiO-66 Catalysts for Efficient Sequential Suzuki Coupling/Asymmetric Aldol Reactions

The design and development of site-isolating and multifunctional catalysts for multistep sequential reactions at the molecular level is a significant challenge. Herein, we first report bifunctional metal NPs?chiral MOFs catalysts for asymmetric sequential reactions. Pd nanoparticles and chiral proline were successfully added to NH2-UiO-66 to construct two chiral bifunctional catalysts, in which active Pd nanoparticles were encapsulated into the frameworks via the "bottle-around-ship" method, and chiral proline was introduced into NH2-UiO-66 by coordination to zirconium nodes and postsynthetic modification (PSM) of the organic linkers. The chiral proline-decorated bifunctional Pd?NH2-UiO-66 catalysts were applied to sequential Suzuki coupling/asymmetric aldol reactions with excellent coupling performance (yields up to 99.9%) and good enantioselectivities (eeanti values up to 97%). The heterogeneous catalyst by coordination of proline can be reused, and the reaction activity was not significantly reduced after four cycles.