138408-62-5Relevant articles and documents
Concise Synthesis of a Potential 5-Lipoxygenase Activating Protein (FLAP) Inhibitor and Its Analogs through Late-Stage Alkene Dicarbofunctionalization
Kc, Shekhar,Dhungana, Roshan K.,Aryal, Vivek,Giri, Ramesh
, p. 1686 - 1694 (2019/07/04)
We report a five-step synthesis of the biologically important 1,1-diarylalkane 1, a potential 5-lipoxygenase activating protein (FLAP) inhibitor that was synthesized previously in 12 steps. In this synthesis, we apply a three-component alkene dicarbofunct