138785-59-8Relevant articles and documents
Asymmetric Catalysis, 77. - New Optically Active Pyrazole Derivatives for Enantioselective Catalysis
Brunner, Henri,Scheck, Thomas
, p. 701 - 710 (2007/10/02)
Starting from the amines 3-6 and the dipyrazolopyrazinedione 2, the optically active (pyrazolylmethyl)amines 11-14 have been synthesized.Furthermore, the preparation of the (+)-camphor-derived optically active pyrazole 17 is described.Pyrazoles 11-13 and 17 are introduced as chiral building blocks into the 2-(1-pyrazolyl)pyridines 30-33.The optically active compounds 23-25 are formed from 2-pyridine and 2,6-bispyridine, respectively, and (+)-3-(bromomethyl)pinane.The pyrazole derivatives 27-29 contain (+)-(1-phenylethyl)hydrazine as the optically active component.Key Words: Pyrazoles, optically active / Pyridines, 2--, 2,6-bis-, 2-(1-pyrazolyl)-