138872-44-3

Basic information

• Product Name: 5-[(BENZOYLAMINO)METHYL]THIOPHENE-2-SULFONYL CHLORIDE
• Synonyms: 5-[(BENZOYLAMINO)METHYL]THIOPHENE-2-SULFONYL CHLORIDE;5-[(BENZOYLAMINO)METHYL]THIOPHENE-2-SULPHONYL CHLORIDE;2-(BENZOYLAMINOMETHYL)THIOPHENE-5-SULFONYLCHLORIDE;5-(benzamidomethyl)thiophene-2-sulfonyl chloride;2-[(Benzoylamino)methyl]-5-(chlorosulphonyl)thiophene, 5-[(Benzoylamino)methyl]-2-(chlorosulphonyl)thiophene, N-{[5-(Chlorosulphonyl)thien-2-yl]methyl}benzamide;5-[N-(Benzoyl)aMinoMethyl]thiophene-2-sulfonyl chloride;5-[(benzoylaMino)Methyl]thiophen-2-sulfonyl chloride;5-(Benzoylamino)methyl-2-thiophenesulfonyl chloride
• CAS NO: 138872-44-3
• Molecular Formula: C12H10ClNO3S2
• Molecular Weight: 315.8
• Mol File: 138872-44-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 123 °C
• Boiling Point: 558.7°C at 760 mmHg
• Flash Point: 291.7°C
• Appearance: /
• Density: 1.457±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 1.62E-12mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-[(BENZOYLAMINO)METHYL]THIOPHENE-2-SULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(BENZOYLAMINO)METHYL]THIOPHENE-2-SULFONYL CHLORIDE(138872-44-3)
• EPA Substance Registry System: 5-[(BENZOYLAMINO)METHYL]THIOPHENE-2-SULFONYL CHLORIDE(138872-44-3)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34-43
• Safety Statements: 26-36/37/39-45-36/37
• RIDADR: 3261
• HazardClass: IRRITANT
• Hazardous Substances Data: 138872-44-3(Hazardous Substances Data)

Usage

Description

5-[(Benzoyl氨基)甲硫基]噻吩-2-磺酰氯是一种有机化合物，具有化学式C12H10ClNO2S2。它是一种重要的中间体，用于合成各种生物活性分子，包括药物和生物分子探针。

Uses

Used in Pharmaceutical Industry:
5-[(Benzoyl氨基)甲硫基]噻吩-2-磺酰氯作为合成中间体，用于开发针对Siglec-8和Siglec-F的靶向药物。这些药物可能有助于调节免疫系统，治疗自身免疫性疾病和炎症性疾病。
Used in Research and Development:
5-[(Benzoyl氨基)甲硫基]噻吩-2-磺酰氯作为化学探针，用于研究Siglec-8和Siglec-F在免疫细胞上的作用机制。这有助于更好地理解这些受体在免疫调节中的功能，为开发新的治疗方法提供科学依据。
Used in Drug Delivery Systems:
5-[(Benzoyl氨基)甲硫基]噻吩-2-磺酰氯可以用于开发新型药物递送系统，以提高药物的靶向性和生物利用度。通过将这种化合物与药物分子结合，可以设计出更有效的药物载体，从而提高治疗效果并减少副作用。

InChI:InChI=1/C12H10ClNO3S2/c13-19(16,17)11-7-6-10(18-11)8-14-12(15)9-4-2-1-3-5-9/h1-7H,8H2,(H,14,15)