139023-12-4Relevant articles and documents
Novel Antagonists of Platelet-Activating Factor. 1. Synthesis and Structure-Activity Relationships of Benzodiazepine and Benzazepine Derivatives of 2-Methyl-1-phenylimidazopyridine
Fray, M. Jonathan,Cooper, Kelvin,Parry, M. John,Richardson, Kenneth,Steele, John
, p. 3514 - 3523 (2007/10/02)
Following the discovery of moderately potent antagonist activity against platelet-activating factor (PAF) in 2-methyl-1-phenylimidazopyridine (2) (IC50=840 nM), 19 derivatives (3-21) were prepared which incorporated various lipophilic groups attach