13907-76-1Relevant articles and documents
THE SYNTHESIS OF ANTINEOPLASTIC AGENTS. XXXII. N-NITROSOUREAS. I.
JOHNSTON,MCCALEB,MONTGOMERY
, p. 669 - 681 (2007/10/04)
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13907-76-1
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Basic information
- Product Name: 1-(2-chloroethyl)-3-(4-methoxyphenyl)-1-nitrosourea
- Synonyms:
- CAS NO:13907-76-1
- Molecular Formula: C10H12ClN3O3
- Molecular Weight: 257.6736
- EINECS: N/A
- Product Categories: N/A
- Mol File: 13907-76-1.mol
- Article Data: 1
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: 1.32g/cm3
- Refractive Index: 1.567
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1-(2-chloroethyl)-3-(4-methoxyphenyl)-1-nitrosourea(CAS DataBase Reference)
- NIST Chemistry Reference: 1-(2-chloroethyl)-3-(4-methoxyphenyl)-1-nitrosourea(13907-76-1)
- EPA Substance Registry System: 1-(2-chloroethyl)-3-(4-methoxyphenyl)-1-nitrosourea(13907-76-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 13907-76-1(Hazardous Substances Data)
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13907-76-1 Usage
Description
1-(2-chloroethyl)-3-(4-methoxyphenyl)-1-nitrosourea, also known as nimustine, is a chemotherapy drug that belongs to the class of alkylating agents. It is characterized by its ability to damage the DNA of cancer cells, leading to their death. Nimustine is primarily used for the treatment of various types of cancer, with a particular focus on brain tumors.Uses
Used in Anticancer Applications:Nimustine is employed as an anticancer agent, specifically for the treatment of brain tumors such as glioblastoma, an aggressive form of brain cancer. It is also effective against other types of tumors. The drug works by damaging the DNA of cancer cells, which ultimately leads to their death. However, it is important to use nimustine under the supervision of a healthcare professional due to its potential for serious side effects, such as nausea, vomiting, and bone marrow suppression.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, nimustine is used as a key component in the development and formulation of cancer treatment drugs. Its alkylating agent properties make it a valuable asset in the fight against various types of cancer, particularly brain tumors. The drug's effectiveness in treating cancer has led to its widespread use in the pharmaceutical sector, where it is continually researched and improved upon to enhance its therapeutic outcomes and minimize side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 13907-76-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.Calculate Digit Verification of CAS Registry Number 13907-76:
(7*1)+(6*3)+(5*9)+(4*0)+(3*7)+(2*7)+(1*6)=111
111 % 10 = 1
So 13907-76-1 is a valid CAS Registry Number.
13907-76-1Upstream product
13907-76-1Downstream Products
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1-(2-chloroethyl)-3-(4-methoxyphenyl)-1-nitrosourea
