1391858-03-9

Basic information

• Product Name: 1-benzyl-5,6-difluoroindoline-2,3-dione
• Synonyms: 1-benzyl-5,6-difluoroindoline-2,3-dione
• CAS NO: 1391858-03-9
• Molecular Weight: 273.239
• Mol File: 1391858-03-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-benzyl-5,6-difluoroindoline-2,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-5,6-difluoroindoline-2,3-dione(1391858-03-9)
• EPA Substance Registry System: 1-benzyl-5,6-difluoroindoline-2,3-dione(1391858-03-9)

Safety Data

• Hazardous Substances Data: 1391858-03-9(Hazardous Substances Data)

Upstream product

• 774-47-0 5,6-difluoro-1H-indole-2,3-dione 
• 100-39-0 benzyl bromide 

Downstream Products

• 1391858-26-6 (2'S,3'R,4'S)-5',5'-diethyl 3',4'-dimethyl 1-benzyl-5,6-difluoro-2-oxospiro[indoline-3,2'-pyrrolidine]-3',4',5',5'-tetracarboxylate 
• 1416217-33-8 1-benzyl-5,6-difluoro-4'-(2-hydroxyphenyl)-6'-methoxy-4'-methyl-3',4'-dihydro-1'H-spiro[indoline-3,2'-quinolin]-2-one 

Relevant articles and documents

Carbene-Catalyzed Enantioselective Aromatic N-Nucleophilic Addition of Heteroarenes to Ketones

The aromatic nitrogen atoms of heteroarylaldehydes are activated by carbene catalysts to react with ketone electrophiles. Multi-functionalized cyclic N,O-acetal products are afforded in good to excellent yields and optical purities. Our reaction involves the formation of an unprecedented aza-fulvene-type acylazolium intermediate. A broad range of N-heteroaromatic aldehydes and electron-deficient ketone substrates works effectively in this transformation. Several of the chiral N,O-acetal products afforded through this protocol exhibit excellent antibacterial activities against Ralstonia solanacearum (Rs) and are valuable in the development of novel agrichemicals for plant protection.