1392116-43-6

Basic information

• Product Name: C₂₄H₂₃F₂N₃O₃
• CAS NO: 1392116-43-6
• Molecular Weight: 439.462
• Mol File: 1392116-43-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₃F₂N₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₃F₂N₃O₃(1392116-43-6)
• EPA Substance Registry System: C₂₄H₂₃F₂N₃O₃(1392116-43-6)

Safety Data

• Hazardous Substances Data: 1392116-43-6(Hazardous Substances Data)

Upstream product

• 302557-44-4 methyl 2,3,4,9-tetrahydro-1H-carbazole-6-carboxylate 
• 36729-27-8 6,7,8,9-tetrahydro-5H-carbazole-3-carboxylic acid 
• 1392116-54-9 C₁₅H₁₅N₃O 
• 2713-34-0 3,5-difluorophenol 
• 1392116-42-5 C₁₈H₁₉N₃O₂ 

Downstream Products

• 1392116-44-7 C₂₄H₂₂F₃N₃O₂ 

Relevant articles and documents

Discovery of ITX 4520: A highly potent orally bioavailable hepatitis C virus entry inhibitor

The manuscript reports an identification of a highly potent, orally bioavailable hepatitis C virus entry inhibitor through optimization of a previously reported class of molecules (1) that were not stable in the rat plasma. Compound 39 (ITX 4520) exhibited an excellent PK profile in both rats and dogs with good oral exposure, half-life and oral bioavailability. The compound is also well-tolerated in the preliminary in vivo toxicity studies and has been selected as a pre-clinical candidate for our HCV clinical pipeline.