139225-06-2

Basic information

• Product Name: N-<(R)-2-hydroxy-1-phenylethyl>-(S)-2-aminobenzeneacetic acid methyl ester
• Synonyms: N-<(R)-2-hydroxy-1-phenylethyl>-(S)-2-aminobenzeneacetic acid methyl ester
• CAS NO: 139225-06-2
• Molecular Weight: 285.343
• Mol File: 139225-06-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-<(R)-2-hydroxy-1-phenylethyl>-(S)-2-aminobenzeneacetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-<(R)-2-hydroxy-1-phenylethyl>-(S)-2-aminobenzeneacetic acid methyl ester(139225-06-2)
• EPA Substance Registry System: N-<(R)-2-hydroxy-1-phenylethyl>-(S)-2-aminobenzeneacetic acid methyl ester(139225-06-2)

Safety Data

• Hazardous Substances Data: 139225-06-2(Hazardous Substances Data)

Upstream product

• 153924-63-1 β-[(phenylmethylene)amino]-[R-(E)-]-benzeneethanol 
• 56613-80-0 D-2-phenylglycinol 
• 139224-87-6 N-<(R)-2-hydroxy-1-phenylethyl>-(S)-α-aminobenzeneacetonitrile 
• 67-56-1 methanol 

Downstream Products

• 142035-32-3 methyl (E)-2-(benzylideneamino)-2-phenylacetate 
• 15028-39-4 L-2-phenylglycine methyl ester hydrochloride 

Relevant articles and documents

α-Phenylglycinol as chiral auxiliary in diastereoselective Strecker synthesis of α-amino acids

The high diastereoselectivity achieved in Strecker synthesis using inexpensive α-phenylglycinol as chiral auxiliary and its facile removal by oxidative clearange make it an ideal choice for the large scale preparations of optically active α-amino acids specially α-arylglycines present abundantly in glycopeptide antibiotics. A number of chiral amino acids are synthesized following this method. Also molecular mechanics calculations are carried out to explain the observed diastereoselection.