1393367-51-5

Basic information

• Product Name: (1-(4-(1H-1,2,4-triazol-1-yl)phenyl)-1H-1,2,3-triazole-4-yl)methanol
• Synonyms: (1-(4-(1H-1,2,4-triazol-1-yl)phenyl)-1H-1,2,3-triazole-4-yl)methanol
• CAS NO: 1393367-51-5
• Molecular Weight: 242.24
• Mol File: 1393367-51-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1-(4-(1H-1,2,4-triazol-1-yl)phenyl)-1H-1,2,3-triazole-4-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1-(4-(1H-1,2,4-triazol-1-yl)phenyl)-1H-1,2,3-triazole-4-yl)methanol(1393367-51-5)
• EPA Substance Registry System: (1-(4-(1H-1,2,4-triazol-1-yl)phenyl)-1H-1,2,3-triazole-4-yl)methanol(1393367-51-5)

Safety Data

• Hazardous Substances Data: 1393367-51-5(Hazardous Substances Data)

Upstream product

• 6219-55-2 1-(4-nitro-phenyl)-1H-[1,2,4]triazole 
• 350-46-9 4-Fluoronitrobenzene 
• 6523-49-5 4-(1,3,4-triazolyl)phenylamine 
• 1393367-46-8 1-(4-azidophenyl)-1H-1,2,4-triazole 
• 107-19-7 propargyl alcohol 

Relevant articles and documents

Synthesis of novel heteroarenes based [1,2,3]-triazoles via click chemistry and their evaluation for antibacterial activity

A series of heteroarenes based [1,2,3]-triazole derivatives 8a-h and 9a-f has been synthesized via click chemistry through Huisgen [2+3] cycloaddition reaction of heteroarylazides 7a-e with alkynes (3a-c, propargyl alcohol or phenyl acetylene) in the presence of CuSO4.5H2O and sodium ascorbate in t-butanol and water (1:1) mixture at 25°C in good to excellent yields (74-94%). All the newly synthesized compounds have been characterized on the basis of analytical and spectral data. The compounds 8a, 8e, 9a, 9b, 9c and 9e have been evaluated for their preliminary in-vitro antibacterial efficacy against a panel of two Gram-positive bacteria viz. Staphylococcus aureus and Streptococcus mutans and two Gramnegative bacteria viz. Escherichia coli and Pseudomonas aeruginosa using the Agar disc diffusion method.