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1394015-42-9

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1394015-42-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1394015-42-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,4,0,1 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1394015-42:
(9*1)+(8*3)+(7*9)+(6*4)+(5*0)+(4*1)+(3*5)+(2*4)+(1*2)=149
149 % 10 = 9
So 1394015-42-9 is a valid CAS Registry Number.

1394015-42-9Downstream Products

1394015-42-9Relevant articles and documents

Fluorescent human EP3 receptor antagonists

Tomasch, Miriam,Schwed, J. Stephan,Kuczka, Karina,Meyer Dos Santos, Sascha,Harder, Sebastian,Nuesing, Rolf M.,Paulke, Alexander,Stark, Holger

, p. 774 - 779 (2012/11/13)

Exchange of the lipophilc part of ortho-substituted cinnamic acid lead structures with different small molecule fluorophoric moieties via a dimethylene spacer resulted in hEP3R ligands with affinities in the nanomolar concentration range. Synthesized compounds emit fluorescence in the blue, green, and red range of light and have been tested concerning their potential as a pharmacological tool. hEP3Rs were visualized by confocal laser scanning microscopy on HT-29 cells, on murine kidney tissues, and on human brain tissues and functionally were characterized as antagonists on human platelets. Inhibition of PGE2 and collagen-induced platelet aggregation was measured after preincubation with novel hEP3R ligands. The pyryllium-labeled ligand 8 has been shown as one of the most promising structures, displaying a useful fluorescence and highly affine hEP3R antagonists.

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