139434-68-7 Usage
Description
N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine is a chemical compound that features a cytidine molecule with a benzoyl group and a methylthiomethyl group attached to its 2'-O and 3',5'-O positions, respectively. It also incorporates a distinctive silicon-containing linker, 1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl, which enhances the cytidine structure. N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine holds promise in the fields of organic chemistry and drug discovery due to its modified nucleoside structure and the unique properties provided by the disiloxane linker. Further studies may reveal its potential biological activities and therapeutic applications.
Uses
Used in Organic Chemistry:
N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine is used as a novel compound for exploring its chemical properties and reactivity in organic synthesis processes.
Used in Drug Discovery:
In the pharmaceutical industry, N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine is used as a potential lead molecule for the development of new drugs, given its unique structure and the possibility of exhibiting biological activities beneficial for therapeutic purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 139434-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,4,3 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 139434-68:
(8*1)+(7*3)+(6*9)+(5*4)+(4*3)+(3*4)+(2*6)+(1*8)=147
147 % 10 = 7
So 139434-68-7 is a valid CAS Registry Number.
139434-68-7Relevant articles and documents
General method for the synthesis of 2′-O-carboranyl-nucleosides
Wojtczak, B?aej,Semenyuk, Andrey,Olejniczak, Agnieszka B.,Kwiatkowski, Marek,Lesnikowski, Zbigniew J.
, p. 3969 - 3972 (2005)
The carboranyl cage is a new modifying entity for nucleosides, DNA oligonucleotides, and other biomolecules. Herein, the first reliable method for the synthesis of nucleosides modified with a carborane cluster at the 2′-position is described.
An azidomethyl protective group in the synthesis of oligoribonucleotides by the phosphotriester method
Efimov,Aralov,Fedunin,Klykov,Chakhmakhcheva
scheme or table, p. 250 - 253 (2010/04/06)
A rapid and effective method of an automatic oligoribonucleotide synthesis alternative to the phosphoramidite one was developed. This method is based on the phosphotriester approach to internucleotide bond formation under intramolecular O-nucleophilic cat
The 4-(N-dichloroacetyl-N-methylamino)benzyloxymethyl group for 2′-hydroxyl protection of ribonucleosides in the solid-phase synthesis of oligoribonucleotides
Cieslak, Jacek,Grajkowski, Andrzej,Kauffman, Jon S.,Duff, Robert J.,Beaucage, Serge L.
, p. 2774 - 2783 (2008/09/20)
(Chemical Equation Presented) Emerging RNA-based technologies for controlling gene expression have triggered a high demand for synthetic oligoribonucleotides and have motivated the development of ribonucleoside phosphoramidites that would exhibit coupling