139645-87-7

Basic information

• Product Name: Glycine, N-(4-nitrobenzoyl)-, hydrazide
• CAS NO: 139645-87-7
• Molecular Formula: C9H10N4O4
• Molecular Weight: 238.203
• Mol File: 139645-87-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Glycine, N-(4-nitrobenzoyl)-, hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-(4-nitrobenzoyl)-, hydrazide(139645-87-7)
• EPA Substance Registry System: Glycine, N-(4-nitrobenzoyl)-, hydrazide(139645-87-7)

Safety Data

• Hazardous Substances Data: 139645-87-7(Hazardous Substances Data)

Upstream product

• 2644-96-4 2-(4-nitrobenzamido)acetic acid methyl ester 
• 122-04-3 4-nitro-benzoyl chloride 
• 7512-77-8 ethyl 2-(4-nitrobenzamido)acetate 

Downstream Products

• 111441-26-0 4-(8,9-dimethoxy-5,6-dihydro-imidazo[5,1-a]isoquinolin-3-yl)-aniline 

Relevant articles and documents

Synthesis and antiviral activities of novel acylhydrazone derivatives targeting HIV-1 capsid protein

HIV-1 capsid protein (CA) plays important roles in the viral replication cycle. A number of acylhydrazone derivatives that act as inhibitors of HIV-1 CA assembly, were designed and synthesized. The synthesized compounds were tested for their antiviral activities and cytotoxicities using CEM cells. Some derivatives also were assayed for their ability to inhibit HIV-1 CA assembly in vitro. Among them, compounds 14f and 14i display the most promising potency with EC50 values of 0.21 and 0.17 μΜ, respectively.