139692-26-5Relevant articles and documents
The Regioselectivity of the Ring Opening of 1-Activated or Nonactivated 2-Alkoxycarbonyl or 2-Cyanoaziridines by Carbanions of the Dicarbonyl Compounds
Bouayad, Zoheir,Chanet-Ray, Josette,Ducher, S.,Vessiere, Roger
, p. 1757 - 1768 (2007/10/02)
Ring opening of title compounds with alkyl malonates, acetylacetone, methyl acetylacetate, and malononitrile was studied.The regioselectivity of the opening depends on several facts.A phenyl group on C-3 favours C-3-N bond cleavage, whereas C-2-N bond cleavage is predominant with C-3-substituted or C-2-H aziridines.Cyanoaziridines are predominantly cleaved at C-3-N.The aziridine configuration at C-2 and C-3 is maintained during the cyclisation in pyrrolidones.