139887-85-7

Basic information

• Product Name: 5'-O-dimethoxytrityl-4-S-pivaloyloxymethyl-4-thiothymidine
• Synonyms: 5'-O-dimethoxytrityl-4-S-pivaloyloxymethyl-4-thiothymidine
• CAS NO: 139887-85-7
• Molecular Weight: 674.815
• Mol File: 139887-85-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5'-O-dimethoxytrityl-4-S-pivaloyloxymethyl-4-thiothymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-dimethoxytrityl-4-S-pivaloyloxymethyl-4-thiothymidine(139887-85-7)
• EPA Substance Registry System: 5'-O-dimethoxytrityl-4-S-pivaloyloxymethyl-4-thiothymidine(139887-85-7)

Safety Data

• Hazardous Substances Data: 139887-85-7(Hazardous Substances Data)

Upstream product

• 7236-57-9 4-thiothymidine 
• 18997-19-8 Chloromethyl pivalate 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 139887-83-5 4-S-pivaloyloxymethyl-4-thiothymidine 

Downstream Products

• 1053261-63-4 C₄₉H₅₇N₄O₁₆PS 
• 125258-56-2 5'-O-(4,4'-Dimethoxytrityl)-4-thiothymidine 
• 1053715-58-4 C₄₉H₅₇N₄O₁₆PS 
• 139887-91-5 5'-O-dimethoxytrityl-4-(S-pivaloyloxymethyl)-4-thiothymidin-3'-yl hydrogenphosphonate 
• 139887-87-9 3'-O-acetyl-5'-O-dimethoxytrityl-4-S-pivaloyloxymethyl-4-thiothymidine 

Relevant articles and documents

Synthesis of Deoxydinucleoside Phosphates Containing 4-Thio Substituted Pyrimidine Nucleobases

The preparations, by the hydrogenphosphonate approach in solution, of the five pyrimidine deoxydinucleoside monophosphates 14a, 14b, 16a, 16b and 17 containing a 4-thiosubstituted pyrimidine nucleobase at either their 3'- or 5'-end are described.These syntheses were conveniently accomplished using 4-thionucleoside derivatives having their sulfur function protected by S-pivaloyloxymethylation.The behaviour of unprotected 4-thionucleoside derivatives was also investigated and they were shown to give comparable overall yields.