13994-57-5

Basic information

• Product Name: 3-METHOXY-3-METHYL-1-BUTYNE
• Synonyms: 3-METHOXY-3-METHYL-1-BUTYNE;3-METHOXY-3-METHYL-BUT-1-YNE
• CAS NO: 13994-57-5
• Molecular Formula: C₆H₁₀O
• Molecular Weight: 98.14
• Mol File: 13994-57-5.mol
• Article Data: 9

Chemical Properties

• Melting Point: -51-2 °C
• Boiling Point: 81-82 °C
• Appearance: /
• Density: 0.8140 g/cm3
• CAS DataBase Reference: 3-METHOXY-3-METHYL-1-BUTYNE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXY-3-METHYL-1-BUTYNE(13994-57-5)
• EPA Substance Registry System: 3-METHOXY-3-METHYL-1-BUTYNE(13994-57-5)

Safety Data

• Hazardous Substances Data: 13994-57-5(Hazardous Substances Data)

Usage

Description

3-Methoxy-3-methyl-1-butyne, also known as MMB, is a chemical compound with the molecular formula C6H12O. It is a clear, colorless liquid characterized by a sharp, fruity odor. MMB is utilized in the production of pharmaceuticals and perfumes due to its distinctive scent and chemical properties.

Uses

Used in Pharmaceutical Industry:
3-Methoxy-3-methyl-1-butyne is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicine.
Used in Perfume Industry:
In the perfume industry, 3-Methoxy-3-methyl-1-butyne is used as a fragrance ingredient. Its sharp, fruity odor makes it a valuable addition to the creation of various scent compositions, enhancing the overall aroma of perfumes and other fragranced products.
Safety Precautions:

Upstream product

• 67-56-1 methanol 
• 1111-97-3 3-chloro-3-methylbut-1-yne 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 

Downstream Products

• 26452-30-2 1-(3-Methoxy-3-methyl-but-1-ynyl)-cyclohexanol 
• 32904-90-8 4-methyl-4-methoxy-1-phenylpent-2-yne-1-one 
• 60214-11-1 3-methoxy-3-methyl-2,4-heptadiyn-1-ol 
• 102171-62-0 4-Methoxy-4-methyl-1,1-diphenyl-pentin-⁽²⁾-ol-⁽¹⁾ 
• 18915-78-1 3.6-Dimethyl-2.6-dimethoxy-2-phenyl-heptin-⁽⁴⁾-ol-⁽³⁾ 
• 132609-13-3 4-Methoxy-4-methyl-1-p-tolyl-pent-2-yn-1-one 
• 89154-38-1 4-Methoxy-4-methyl-1-(4-nitro-phenyl)-pent-2-yn-1-one 
• 933-52-8 2,2,4,4-tetramethyl-1,3-cyclobutanedione 
• 84022-47-9 2,6-dimethyl-6-methoxy-4-heptyn-3-one 
• 113792-94-2 3-methoxy-3-methylbutynyl benzoate 
• 3197-68-0 2-(1-Cyclohexenyl)ethanol 
• 83043-81-6 12,20-trimethylene-10,14-retro-retinyl tert-butyldimethylsilyl ether 
• 84303-95-7 2,2,5-trimethyl-5-(2',6',6'-trimethyl-1'-cyclohexen-1'-yl)-3,4,6(E)-heptatriene 
• 21336-32-3 1-(2-hydroxyethyl)cyclohept-1-ene 

Relevant articles and documents

Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure- based drug design

A series of novel allosteric antagonists of the GLP-1 receptor (GLP-1R), exemplified by HTL26119, are described. SBDD approaches were employed to identify HTL26119, exploiting structural understanding of the allosteric binding site of the closely related Glucagon receptor (GCGR) (Jazayeri et al., 2016) and the homology relationships between GCGR and GLP-1R. The region around residue C3476.36b of the GLP-1R receptor represents a key difference from GCGR and was targeted for selectivity for GLP-1R.

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Palladium-Catalyzed [2+1] Cycloadditions Affording Vinylidenecyclopropanes as Precursors of 7-Membered Carbocycles

Palladium(II) acetate in association with secondary phosphine oxides provides an efficient catalytic system for [2+1] cycloadditions starting from oxanorbornene derivatives and tertiary propargyl esters giving rise to vinylidenecyclopropanes. This reaction is specific to bidentate phosphinito-phosphinous acid ligands generated from secondary phosphine oxides. The [2+1] cycloaddition was found broad in scope with a high tolerance to various functional groups. Moreover, vinylidenecyclopropanes were straightforwardly converted into oxabicyclo[3.2.1]oct-2-ene derivatives through a palladium-catalyzed ring-expansion. Finally, the oxa bridge cleavage of oxatricyclic compounds yields functionalized 7-membered carbocycles.