140176-27-8

Basic information

• Product Name: 4-Oxo-1,3-piperidinedicarboxylic acid
• Synonyms: 4-Oxo-1,3-piperidinedicarboxylic acid
• CAS NO: 140176-27-8
• Molecular Formula: C₁₅H₁₇NO₅
• Molecular Weight: 187.15006
• Mol File: 140176-27-8.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Oxo-1,3-piperidinedicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxo-1,3-piperidinedicarboxylic acid(140176-27-8)
• EPA Substance Registry System: 4-Oxo-1,3-piperidinedicarboxylic acid(140176-27-8)

Safety Data

• Hazardous Substances Data: 140176-27-8(Hazardous Substances Data)

Upstream product

• 71486-53-8 methyl 4-oxo-3-piperidinecarboxylate hydrochloride 
• 501-53-1 benzyl chloroformate 
• 108554-34-3 methyl 4-oxonipecotate 

Downstream Products

• 140176-28-9 1-(carbobenzyloxy)-3-carbomethoxy-3-(phenylselenyl)-4-piperidone 
• 135967-34-9 1-(carbobenzyloxy)-3-carbomethoxy-5,6-dihydro-4-pyridone 
• 189947-44-2 1,4-Dithia-8-aza-spiro[4.5]decane-6,8-dicarboxylic acid 8-benzyl ester 6-methyl ester 
• 189947-48-6 benzyl 6-[(tert-butoxycarbonyl)amino]-1,4-dithia-8-azaspiro[4.5]decane-8-carboxylate 
• 135967-35-0 2-n-butyl-1-(carbobenzyloxy)-3-carbomethoxy-4-piperidone 
• 135967-40-7 2-n-butyl-1-(carbobenzyloxy)-3-carbomethoxy-3-methyl-4-piperidone 
• 135967-41-8 2-n-butyl-1-(carbobenzyloxy)-3-carbomethoxy-3-methyl-4-piperidone ethylene ketal 
• 135967-38-3 1-(carbobenzyloxy)-3-carbomethoxy-2-<4,8,12-trimethyl-3(E),7(E),11-tridecatrienyl>-4-piperidone 
• 135967-39-4 1-(carbobenzyloxy)-3-carbomethoxy-2-<3,8,12,16-tetramethyl-3(E),7(E),8(E),11(E),15-heptadecatrienyl>-4-piperidone 
• 140176-30-3 2-n-butyl-1,3-dimethyl-3-<<(p-toluenesulfonyl)oxy>methyl>-4-piperidone ethylene ketal 
• 140176-45-0 1-(carbobenzyloxy)-2-<4,8,12-trimethyl-3(E),7(E),11-tridecatrienyl>-4-piperidone 
• 140176-49-4 1-(carbobenzyloxy)-2-<3,8,12,16-tetramethyl-3(E),7(E),11(E),15-heptadecatetraenyl>-4-piperidone 
• 135967-36-1 2-Benzyl-4-oxo-piperidine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester 
• 135967-37-2 2-[(E)-5-(tert-Butyl-dimethyl-silanyloxy)-3-methyl-pent-3-enyl]-4-oxo-piperidine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester 

Relevant articles and documents

BICYCLIC AMINES AS NOVEL JAK KINASE INHIBITORS

The present invention relates to a compound according to formula (I) wherein R1 represents alkyl; n is 1 or 2; R2 is selected from the group consisting of hydrogen, cyano, -SO2Ra, -SO2NRbR

2-[BIS(4-FLUOROPHENYL)METHYL]-2,7-DIAZASPIRO[4.5]DECAN-10-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE HUMAN DOPAMINE-ACTIVE-TRANSPORTER (DAT) PROTEIN FOR THE TREATMENT OF E.G. ATTENTION DEFICIT DISORDER (ADD)

The present invention provides compounds of formula (I) and in particular 2-[bis(4-fluorophenyl)methyl]-2,7- diazaspiro[4.5]decan-10-one derivatives and related compounds as inhibitors of human dopamine-active-transporter (DAT) protein for the treatment of sexual dysfunction, affective disorders, anxiety, depression, chronic fatigue, Tourette syndrome, Angelman syndrome, attention deficit disorder (ADD), attention deficit hyperactivity disorder (ADHD), obesity, pain, obsessive-compulsive disorder, movement disorders, CNS disorders, sleep disorders, narcolepsy, conduct disorder, substance abuse (including smoking cessation), eating disorders, and impulse control disorders.

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