1402079-19-9

Basic information

• Product Name: (E)-ethyl 3-((6R,6aR,7R,8R,9S,10aS)-2-bromo-10,10-dicyano-7-hydroxy-6,9-diphenyl-6a,7,8,9,10,10a-hexahydro-6H-isoindolo[2,1-a]indol-8-yl)acrylate
• CAS NO: 1402079-19-9
• Molecular Weight: 606.519
• Mol File: 1402079-19-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-ethyl 3-((6R,6aR,7R,8R,9S,10aS)-2-bromo-10,10-dicyano-7-hydroxy-6,9-diphenyl-6a,7,8,9,10,10a-hexahydro-6H-isoindolo[2,1-a]indol-8-yl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-ethyl 3-((6R,6aR,7R,8R,9S,10aS)-2-bromo-10,10-dicyano-7-hydroxy-6,9-diphenyl-6a,7,8,9,10,10a-hexahydro-6H-isoindolo[2,1-a]indol-8-yl)acrylate(1402079-19-9)
• EPA Substance Registry System: (E)-ethyl 3-((6R,6aR,7R,8R,9S,10aS)-2-bromo-10,10-dicyano-7-hydroxy-6,9-diphenyl-6a,7,8,9,10,10a-hexahydro-6H-isoindolo[2,1-a]indol-8-yl)acrylate(1402079-19-9)

Safety Data

• Hazardous Substances Data: 1402079-19-9(Hazardous Substances Data)

Upstream product

• 53590-50-4 5-bromo-1H-indole-2-carbaldehyde 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Relevant articles and documents

Quadruple domino organocatalysis: An asymmetric aza-Michael/Michael/ Michael/Aldol reaction sequence leading to tetracyclic indole structures with six stereocenters

Quadruple domino/Wittig-one pot: An organocatalytic, asymmetric, three-component quadruple cascade, which leads to tetracyclic double-annulated indole derivatives, is described. The domino products were further derivatized by aldehyde olefination under one-pot conditions to obtain complex isoindolo[2, 1-a]indole derivatives bearing six stereogenic centers in a highly stereoselective fashion. Copyright