14049-03-7 Usage
Description
3-Deoxy-3-fluoro-D-glucose (CAS# 14049-03-7) is a white to light yellow crystalline powder that serves as a valuable compound in the realm of organic synthesis. It is a modified form of D-glucose, a naturally occurring sugar, with a fluorine atom replacing one of the hydroxyl groups at the 3-position. This modification grants it unique chemical properties that make it a versatile building block for various applications.
Uses
Used in Organic Synthesis:
3-Deoxy-3-fluoro-D-glucose is used as a synthetic building block for the creation of various complex organic molecules. Its unique chemical properties allow for the development of novel compounds with potential applications in pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-deoxy-3-fluoro-D-glucose is utilized as a key intermediate in the synthesis of new drugs. Its distinct chemical structure can be exploited to design and develop innovative therapeutic agents with improved efficacy and selectivity.
Used in Research and Development:
3-Deoxy-3-fluoro-D-glucose is also employed as a research tool in academic and industrial laboratories. It can be used to study the effects of sugar modifications on biological processes and to develop new methodologies for the synthesis of complex carbohydrates and their derivatives.
Used in Diagnostic Applications:
Due to its structural similarity to glucose, 3-deoxy-3-fluoro-D-glucose can be used in the development of diagnostic tools and imaging agents for various diseases, particularly those involving altered glucose metabolism, such as diabetes and cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 14049-03-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,0,4 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 14049-03:
(7*1)+(6*4)+(5*0)+(4*4)+(3*9)+(2*0)+(1*3)=77
77 % 10 = 7
So 14049-03-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H11FO5/c7-3-4(9)2(1-8)12-6(11)5(3)10/h2-6,8-11H,1H2/t2-,3+,4-,5-,6?/m1/s1
14049-03-7Relevant articles and documents
3-Fluoroazetidinecarboxylic Acids and trans,trans- 3,4-Difluoroproline as Peptide Scaffolds: Inhibition of Pancreatic Cancer Cell Growth by a Fluoroazetidine Iminosugar
Liu, Zilei,Jenkinson, Sarah F.,Vermaas, Tom,Adachi, Isao,Wormald, Mark R.,Hata, Yukako,Kurashima, Yukiko,Kaji, Akira,Yu, Chu-Yi,Kato, Atsushi,Fleet, George W. J.
, p. 4244 - 4258 (2015/05/13)
Reverse aldol opening renders amides of 3-hydroxyazetidinecarboxylic acids (3-OH-Aze) unstable above pH 8. Aze, found in sugar beet, is mis-incorporated for proline in peptides in humans and is associated with multiple sclerosis and teratogenesis. Aze-con
