1405128-56-4Relevant articles and documents
BICYCLIC PYRIDAZINE COMPOUNDS AS PIM INHIBITORS
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Page/Page column 109, (2012/11/13)
The invention relates to bicyclic compounds of formulas I and I', and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of Pim kinase related conditions and diseases, preferably cancer.