1408236-64-5

Basic information

• Product Name: 4,4,4-trifluoro-1,3-bis(4-fluorophenyl)butan-1-one
• Synonyms: 4,4,4-trifluoro-1,3-bis(4-fluorophenyl)butan-1-one
• CAS NO: 1408236-64-5
• Molecular Weight: 314.255
• Mol File: 1408236-64-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,4,4-trifluoro-1,3-bis(4-fluorophenyl)butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,4-trifluoro-1,3-bis(4-fluorophenyl)butan-1-one(1408236-64-5)
• EPA Substance Registry System: 4,4,4-trifluoro-1,3-bis(4-fluorophenyl)butan-1-one(1408236-64-5)

Safety Data

• Hazardous Substances Data: 1408236-64-5(Hazardous Substances Data)

Upstream product

• 462-06-6 fluorobenzene 
• 406-94-0 4,4,4-trifluorobut-2-enoic acid 

Relevant articles and documents

Efficient synthesis of trifluoromethylated dihydrochalcones, aryl vinyl ketones and indanones by superelectrophilic activation of 4,4,4-trifluoro/3- (trifluoromethyl)crotonic acids

Superacid catalyzed electrophilic substitution of arenes using 4,4,4,-trifluoro/3-trifluoromethylcrotonic acids has been investigated. The direct synthesis of various trifluoromethylated dihydrochalcones, aryl vinyl ketones and indanones has been achieved by this methodology. It has been found that the position of the trifluoromethyl group has a profound effect on the nature of the reaction and the products. In the pharmaceutical industry, many fluoroorganics are shown to possess significant biological and therapeutic activities. Therefore, these novel compounds can be considered key intermediates for the preparation of potential biologically active molecules.