1408661-07-3

Basic information

• Product Name: C₁₂H₇ClFN₃
• CAS NO: 1408661-07-3
• Molecular Weight: 247.659
• Mol File: 1408661-07-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₇ClFN₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₇ClFN₃(1408661-07-3)
• EPA Substance Registry System: C₁₂H₇ClFN₃(1408661-07-3)

Safety Data

• Hazardous Substances Data: 1408661-07-3(Hazardous Substances Data)

Upstream product

• 54-96-6 3,4-diaminopyridine 
• 394-30-9 5-chloro-2-fluorobenzoic acid 

Relevant articles and documents

Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: Further optimization of anti-hepatitis C virus activity

Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines represent a novel class of compounds with activity against pestiviruses and the hepatitis C virus (HCV). Several series of analogues with modifications of the substituents in positions 2 and 5 were prepared. These efforts resulted in the discovery of several compounds with potent antiviral activity of which 2-(2,3-difluorophenyl)-5-[4-(trifluoromethyl)benzyl]-5H-imidazo[4,5-c]pyridine (46) was most potent against HCV (EC50 of 0.10 μM and a selectivity index of 1080).