140928-03-6

Basic information

• Product Name: 18-acetoxy-25-<(trimethylsilyl)oxy>-1α-<(tert-butyldimethylsilyl)oxy>vitamin D3 tert-butyldimethylsilyl ether
• Synonyms: 18-acetoxy-25-<(trimethylsilyl)oxy>-1α-<(tert-butyldimethylsilyl)oxy>vitamin D3 tert-butyldimethylsilyl ether
• CAS NO: 140928-03-6
• Molecular Weight: 775.389
• Mol File: 140928-03-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 18-acetoxy-25-<(trimethylsilyl)oxy>-1α-<(tert-butyldimethylsilyl)oxy>vitamin D3 tert-butyldimethylsilyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 18-acetoxy-25-<(trimethylsilyl)oxy>-1α-<(tert-butyldimethylsilyl)oxy>vitamin D3 tert-butyldimethylsilyl ether(140928-03-6)
• EPA Substance Registry System: 18-acetoxy-25-<(trimethylsilyl)oxy>-1α-<(tert-butyldimethylsilyl)oxy>vitamin D3 tert-butyldimethylsilyl ether(140928-03-6)

Safety Data

• Hazardous Substances Data: 140928-03-6(Hazardous Substances Data)

Upstream product

• 140927-96-4 De-A,B-8α,18-diacetoxycholestane 
• 140927-98-6 De-A,B-18-acetoxy-25-hydroxy-8-cholestanone 
• 140927-97-5 De-A,B-18-acetoxy-8α-cholestanol 
• 66251-18-1 Grundmann's ketone 
• 33813-99-9 Grundmann's alcohol 
• 81522-68-1 [(2Z)-2-[(3S,5R)-3,5-bis(tert-butyldimethylsilanyloxy)-2-methylenecyclohexylidene]ethyl]diphenylphosphine oxide 
• 140927-99-7 De-A,B-18-acetoxy-25-<(trimethylsilyl)oxy>-8-cholestanone 

Downstream Products

• 140927-93-1 18-acetoxy-1alpha,25-dihydroxycholecalciferol 

Relevant articles and documents

18-Substituted Derivatives of Vitamin D: 18-Acetoxy-1α,25-dihydroxyvitamin D3 and Related Analogues

The bridged ether 6, produced via light-induced lead tetraacetate oxidation of Grundmann's alcohol 5, was transformed in three to four steps to the CD-ring ketones 9b and 10 which were then transformed via Horner-Wittig coupling to the 18-acetoxy analogue