141-21-9

Basic information

• Product Name: N-[2-[(2-hydroxyethyl)amino]ethyl]stearamide
• Synonyms: N-[2-[(2-hydroxyethyl)amino]ethyl]stearamide;STEARAMIDOETHYL ETHANOLAMINE;Octadecanamide, N-2-(2-hydroxyethyl)aminoethyl-;2-(2-stearamidoethylamino)-Ethanol;N-(Ethoxyaminoethyl)stearamide;N-[2-[(2-hydroxyethyl) amino]ethyl]-Octadecanamide;Stearic N-(aminoethyl)ethanolamide;N-[2-[(2-Hydroxyethyl)amino]ethyl]stearic acid amide
• CAS NO: 141-21-9
• Molecular Formula: C₂₂H₄₆N₂O₂
• Molecular Weight: 370.61284
• EINECS: 205-469-7
• Mol File: 141-21-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 543.4 °C at 760 mmHg
• Flash Point: 282.4 °C
• Appearance: /
• Density: 0.917 g/cm³
• Vapor Pressure: 4.51E-14mmHg at 25°C
• Refractive Index: 1.47
• CAS DataBase Reference: N-[2-[(2-hydroxyethyl)amino]ethyl]stearamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-[(2-hydroxyethyl)amino]ethyl]stearamide(141-21-9)
• EPA Substance Registry System: N-[2-[(2-hydroxyethyl)amino]ethyl]stearamide(141-21-9)

Safety Data

• Hazardous Substances Data: 141-21-9(Hazardous Substances Data)

Usage

General Description

N-[2-[(2-hydroxyethyl)amino]ethyl]stearamide is a chemical compound that belongs to the amide group, consisting of a stearic acid molecule linked to a hydroxyethylamine. It is widely used in various industries, including personal care, cosmetics, and pharmaceuticals, as an emulsifying agent, thickening agent, and surfactant. This chemical is a versatile ingredient known for its ability to stabilize and improve the texture of products, as well as enhancing the solubility of other ingredients. With its emollient properties, N-[2-[(2-hydroxyethyl)amino]ethyl]stearamide is commonly found in skin and hair care products, where it helps to moisturize and condition the skin and hair. Additionally, it acts as a lubricant and prevents products from separating, making it an important component in many formulations.

InChI:InChI=1/C22H46N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26)24-19-18-23-20-21-25/h23,25H,2-21H2,1H3,(H,24,26)

Synthetic route

2-(2-Aminoethylamino)ethanol (111-41-1) + stearic acid (57-11-4) → [2-(2-hydroxyethylamino)ethyl]heptadecylamide (141-21-9)

Conditions	Yield
With calcium oxide at 140℃; for 0.0666667h; microwave irradiation;	92%

stearic acid ethyl ester (111-61-5) + 2-(2-Aminoethylamino)ethanol (111-41-1) → [2-(2-hydroxyethylamino)ethyl]heptadecylamide (141-21-9)

Conditions	Yield
at 130 - 230℃;

[2-(2-hydroxyethylamino)ethyl]heptadecylamide (141-21-9) → 2-heptadecyl-1-(2-hydroxyethyl)-2-imidazoline (95-19-2)

Conditions	Yield
at 220℃; for 4h;

Upstream product

• 111-41-1 2-(2-Aminoethylamino)ethanol 
• 57-11-4 stearic acid 
• 111-61-5 stearic acid ethyl ester 

Downstream Products

• 95-19-2 2-heptadecyl-1-(2-hydroxyethyl)-2-imidazoline 

Relevant articles and documents

Synthesis and properties of a series of CO2 switchable surfactants with imidazoline group

Switchable surfactants are environment-friendly compounds, which can be separated from the system or lose surface activity after completing their function during one stage of a process. In order to study switchable properties of a kind of CO2 switchable surfactant with an imidazoline group, four 2-alkyl-1-hydroxyethylimidazolines were synthesized by condensation of N-(2-hydroxyethyl)ethanediamine with dodecanoic, tetradecanoic, hexadecanoic, and octadecanoic acids. Then, the series of long-chain alkyl imidazoline compounds were reacted with dry ice to produce imidazolinium bicarbonates cationic surfactants. The critical micelle concentration (CMC) and surface tension at CMC (γcmc) measured by the Wilhelmy plate technique show that these surfactants have excellent surface activity. The changes of conductivity before and after bubbling CO2 show the conversion between imidazolines and imidazolinium bicarbonates cationic surfactants. Conductivity cycles indicated that these surfactants could be switched by CO2 reversibly and repeating this three times. However, their switchable function on the emulsification-demulsification of water-alkane was dissatisfactory due to the emulsibility of amide which was hydrolyzed from 2-alkyl-1-hydroxyethylimidazoline. Therefore, the application of these switchable surfactants needed to be studied further.