141031-77-8Relevant articles and documents
Synthesis of a ketorolac model via aromatic carbenoid insertion
Mueller, Paul,Polleux, Philippe
, p. 317 - 323 (2007/10/03)
The decomposition of diazo ester 2b with chiral Rh(II) catalysts proceeded via intramolecular aromatic carbenoid insertion to the racemic pyrrole derivative 5b in 72% yield. In contrast, the benzoylated precursor 16 afforded no ketorolac 1b when exposed t
Process for preparing 5-aroyl-2,3-dihydro-1H-pyrrolizine-1,1-dicarboxylates (I) and intermediates therefor
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, (2008/06/13)
5-Aroyl-2,3-dihydro-1H-pyrrolizine-1,1-dicarboxylates of the formula STR1 are prepared from 2-aroylpyrroles. Hydrolysis and mono-decarboxylation of these compounds affords ketorolac and related compounds.