14110-97-5 Usage
Description
4-(CHLOROMERCURI)BENZENESULFONIC ACID, SODIUM SALT is a chemical compound that serves as a useful sulfhydryl reagent. It is an off-white powder in appearance and is known for its reactivity with Histidine 225C, a residue of the NhaA-Na/H Antiporter of Escherichia Coli. 4-(CHLOROMERCURI)BENZENESULFONIC ACID, SODIUM SALT is more soluble than p-chloromercuribenzoic acid, making it a preferred choice in certain applications.
Uses
Used in Biochemical Research:
4-(CHLOROMERCURI)BENZENESULFONIC ACID, SODIUM SALT is used as a sulfhydryl reagent for studying the interactions and properties of proteins and other biomolecules. Its application in this field is due to its ability to react with specific amino acid residues, such as Histidine 225C, providing valuable insights into the structure and function of proteins.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-(CHLOROMERCURI)BENZENESULFONIC ACID, SODIUM SALT is used as a reagent for the development and synthesis of various drugs. Its reactivity with sulfhydryl groups makes it a valuable tool in the design and modification of drug molecules, potentially leading to the creation of new therapeutic agents.
Used in Environmental Science:
4-(CHLOROMERCURI)BENZENESULFONIC ACID, SODIUM SALT is employed as a reagent in environmental science for the detection and analysis of pollutants and contaminants. Its ability to react with specific chemical groups can help in identifying and quantifying harmful substances in the environment, contributing to the development of effective pollution control strategies.
Used in Analytical Chemistry:
In analytical chemistry, 4-(CHLOROMERCURI)BENZENESULFONIC ACID, SODIUM SALT is used as a reagent for the identification and quantification of various compounds. Its solubility and reactivity with specific functional groups make it a useful tool in the development of analytical methods and techniques for chemical analysis.
Purification Methods
The free acid is obtained by acidifying an aqueous solution, filtering off the acid, washing it with H2O and recrystallising from hot H2O to give a colourless solid which is dried in a vacuum over P2O5 and should be free of Cl-ions (AgNO3 test). The Na salt is made by dissolving it in one equivalent of aqueous NaOH and evaporating to dryness. [Nesmejanow et al. Chem Ber 67 130 1934, Boyer J Am Chem Soc 76 4331 1954.] HIGHLY TOXIC.
Check Digit Verification of cas no
The CAS Registry Mumber 14110-97-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,1,1 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 14110-97:
(7*1)+(6*4)+(5*1)+(4*1)+(3*0)+(2*9)+(1*7)=65
65 % 10 = 5
So 14110-97-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H5O3S.ClH.Hg.Na/c7-10(8,9)6-4-2-1-3-5-6;;;/h2-5H,(H,7,8,9);1H;;/q;;2*+1/p-2/rC6H5ClHgO3S.Na/c7-8-5-1-3-6(4-2-5)12(9,10)11;/h1-4H,(H,9,10,11);/q;+1/p-1
