141330-90-7

Basic information

• Product Name: 2,2-Dimethyl-propionic acid (2R,3R,4S,5S,6R)-2-{[(R)-(diethoxy-phosphoryl)-p-tolyl-methyl]-amino}-3,5-bis-(2,2-dimethyl-propionyloxy)-6-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-4-yl ester
• Synonyms: 2,2-Dimethyl-propionic acid (2R,3R,4S,5S,6R)-2-{[(R)-(diethoxy-phosphoryl)-p-tolyl-methyl]-amino}-3,5-bis-(2,2-dimethyl-propionyloxy)-6-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-4-yl ester
• CAS NO: 141330-90-7
• Molecular Weight: 755.884
• Mol File: 141330-90-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,2-Dimethyl-propionic acid (2R,3R,4S,5S,6R)-2-{[(R)-(diethoxy-phosphoryl)-p-tolyl-methyl]-amino}-3,5-bis-(2,2-dimethyl-propionyloxy)-6-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-4-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Dimethyl-propionic acid (2R,3R,4S,5S,6R)-2-{[(R)-(diethoxy-phosphoryl)-p-tolyl-methyl]-amino}-3,5-bis-(2,2-dimethyl-propionyloxy)-6-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-4-yl ester(141330-90-7)
• EPA Substance Registry System: 2,2-Dimethyl-propionic acid (2R,3R,4S,5S,6R)-2-{[(R)-(diethoxy-phosphoryl)-p-tolyl-methyl]-amino}-3,5-bis-(2,2-dimethyl-propionyloxy)-6-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-4-yl ester(141330-90-7)

Safety Data

• Hazardous Substances Data: 141330-90-7(Hazardous Substances Data)

Upstream product

• 120255-29-0 C₃₄H₅₁NO₉ 
• 762-04-9 phosphonic acid diethyl ester 
• 104-87-0 4-methyl-benzaldehyde 
• 108342-87-6 tetra-O-pivaloyl-β-D-galactopyranosylamine 

Relevant articles and documents

Glycosylation-induced and Lewis acid-catalyzed asymmetric synthesis of β-N-glycosidically linked α-aminophosphonic acids derivatives

The diastereospecific formation of β-N-glycosidically linked α-aminophosphonic acids derivatives has been achieved with high yield via a Mannich-type reaction. The reaction was performed by using O-pivaloylated galactosylamine 1 as a chiral template and boron trifluoride diethyl etherate as a catalyst in THF. Imines 3 of aromatic compounds and diethyl phosphite were converted to N-galactosyl α-aminoalkylphosphonate 4, giving ratios of diastereomers higher than 19:1. This procedure provides a rapid access to biologically important galactosyl α-aminophosphonic acids derivatives.