141392-23-6 Usage
Description
Rapamycin, 32-O-demethyl-, also known as Rapamycin derivative, is a macrocyclic lactone compound derived from the natural product rapamycin, produced by the bacterium Streptomyces hygroscopicus. It possesses potent immunosuppressant and antiproliferative properties, making it a promising pharmaceutical candidate for various applications.
Uses
Used in Oncology:
Rapamycin, 32-O-demethylis used as an anticancer agent for the treatment of certain types of cancer. Its ability to inhibit the activity of the protein complex mTOR (mechanistic target of rapamycin), which is involved in cell growth and proliferation, makes it effective in controlling tumor growth and preventing cancer progression.
Used in Organ Transplantation:
Rapamycin, 32-O-demethylis used as an immunosuppressant in the prevention of organ transplant rejection. Its immunosuppressive properties help to reduce the risk of the recipient's immune system attacking the transplanted organ, thereby increasing the success rate of organ transplants.
Used in Neurological Disorders:
Rapamycin, 32-O-demethylhas shown potential in the treatment of certain neurological disorders. Its ability to modulate cellular processes involved in neurodegeneration and neuroprotection makes it a promising candidate for the management of conditions such as Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.
Used in Aging-Related Conditions:
Rapamycin, 32-O-demethylhas demonstrated potential in the treatment of aging-related conditions. Its antiproliferative and immunosuppressive properties may contribute to the delay of aging processes and the improvement of overall health and longevity in individuals.
Check Digit Verification of cas no
The CAS Registry Mumber 141392-23-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,3,9 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 141392-23:
(8*1)+(7*4)+(6*1)+(5*3)+(4*9)+(3*2)+(2*2)+(1*3)=106
106 % 10 = 6
So 141392-23-6 is a valid CAS Registry Number.
