1415-73-2 Usage
Description
Aloin is a naturally occurring C-glycosyl compound found in various Aloe plant species, characterized by its lemon yellow crystalline powder appearance. It is a beta-D-glucopyranose in which the anomeric hydroxy group is replaced by a specific anthracenyl moiety. Aloin was traditionally used as a laxative for the treatment of constipation, and recent studies have explored its potential as an antineoplastic agent that enhances melanogenesis and transglutaminase activity.
Uses
Used in Pharmaceutical Industry:
Aloin is used as a stimulant-laxative for the treatment of constipation due to its natural occurrence in Aloe plant species and its historical use in this application.
Used in Anticancer Applications:
Aloin is being investigated as an antineoplastic agent, particularly for its potential to enhance melanogenesis and transglutaminase activity. This application is still under research, and its effectiveness in cancer treatment is yet to be fully established.
Used in Cosmetics Industry:
Given its potential to enhance melanogenesis, Aloin may also find use in the cosmetics industry for products aimed at improving skin pigmentation and promoting an even skin tone. However, further research and development are necessary to confirm its safety and efficacy in this application.
Safety Profile
Poison by subcutaneous andintravenous routes. Moderately toxic by ingestion. Whenheated to decomposition it emits acrid smoke and fumes.A carthartic and purgative.
Purification Methods
Aloin forms the monohydrate as lemon yellow crystals on crystallisation from H2O (450g/1.5L) which has a lower m ~70-80o than the anhydrous substance. [Cahn & Simonsen J Chem Soc 2573 1932, Hay & Haynes J Chem Soc 3141 1956.]
Check Digit Verification of cas no
The CAS Registry Mumber 1415-73-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,1 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1415-73:
(6*1)+(5*4)+(4*1)+(3*5)+(2*7)+(1*3)=62
62 % 10 = 2
So 1415-73-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H22O9/c22-6-8-4-10-14(21-20(29)19(28)17(26)13(7-23)30-21)9-2-1-3-11(24)15(9)18(27)16(10)12(25)5-8/h1-5,13-14,17,19-26,28-29H,6-7H2/t13-,14?,17-,19+,20-,21+/m1/s1