141524-76-7 Usage
Derivative of imidazole
Yes, it is a derivative of imidazole
Contains a methyl group
Yes, it has a methyl group
Contains a phenylthio group
Yes, it has a phenylthio group
Pharmaceutical properties
Yes, it has shown potential pharmaceutical properties
Fields of pharmaceutical application
Drug development and medicinal chemistry
Utility in organic synthesis
Yes, it may have utility in organic synthesis
Use as a building block
Yes, it could serve as a building block for the preparation of more complex chemical compounds
Biological activity
Potential, it may possess biological activity
Starting point for drug development
Yes, it could serve as a starting point for the development of new drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 141524-76-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,5,2 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 141524-76:
(8*1)+(7*4)+(6*1)+(5*5)+(4*2)+(3*4)+(2*7)+(1*6)=107
107 % 10 = 7
So 141524-76-7 is a valid CAS Registry Number.
141524-76-7Relevant articles and documents
Preparatory study for the synthesis of the starfish alkaloid imbricatine. Syntheses of 5-arylthio-3-methyl-L-histidines
Ohba,Mukaihira,Fujii
, p. 1784 - 1790 (2007/10/02)
Chiral syntheses of 3-methyl-5-(phenylthio)-L-histidine (8a) and 3-methyl-5-(1-naphthalenylthio)-L-histidine (8b), selected as models for the asteroid alkaloid imbricatine (7), have been accomplished through a 10-step route starting from 4(5)-bromoimidazole (9). The key steps involved were methylation of 9, hydroxymethylation of 4-bromo-1-methyl-1H-imidazole (11), replacement of the 4-bromo group by an arylthio group in the aldehyde 14, and introduction of a chiral α-amino acid moiety into the chlorides 17a and 17b by the 'bis-lactim ether' method. The synthesis of the 4-(4-methoxybenzyl)thio analogue 17c, carried out in a similar manner, concluded formal syntheses of ovothiols A and C (1 and 3).