1415387-18-6

Basic information

• Product Name: 4-hydrazinyl-3-(methylsulfanyl)-1-phenyl-pyrazolo[3,4-d]pyrimidine
• CAS NO: 1415387-18-6
• Molecular Weight: 272.333
• Mol File: 1415387-18-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-hydrazinyl-3-(methylsulfanyl)-1-phenyl-pyrazolo[3,4-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydrazinyl-3-(methylsulfanyl)-1-phenyl-pyrazolo[3,4-d]pyrimidine(1415387-18-6)
• EPA Substance Registry System: 4-hydrazinyl-3-(methylsulfanyl)-1-phenyl-pyrazolo[3,4-d]pyrimidine(1415387-18-6)

Safety Data

• Hazardous Substances Data: 1415387-18-6(Hazardous Substances Data)

Upstream product

• 91974-70-8 3-methylsulphanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one 
• 1415387-16-4 4-chloro-3-methylsulphanyl-1-phenyl-pyrazolo[3,4-d]pyrimidine 

Downstream Products

• 1415387-20-0 4-[2-(4-aminobenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1415387-21-1 4-[2-(4-bromobenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1415387-22-2 4-[2-(4-chlorobenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1415387-23-3 4-[2-(4-fluorobenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1415387-24-4 4-[2-(2-hydroxybenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1415387-25-5 4-[2-(3-fydroxybenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1415387-26-6 4-[2-(4-hydroxybenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1415387-27-7 4-[2-(3-methoxybenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1415387-28-8 4-[2-(2-chloro-4-nitrobenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 

Relevant articles and documents

Synthesis of novel pyrazolo[3,4-d]pyrimidine derivatives as potential anti-breast cancer agents

A series of new 1-aryl-4-benzylidenehydrazinyl-3-methylsulphanyl- pyrazolo[3,4-d]pyrimidines 6a-p was synthesized. The cytotoxic activity of the newly synthesized compounds against human breast cancer cell line, MCF7 was investigated. Most of the test compounds showed potent antitumor activity comparable to that of doxorubicin. The 1-phenyl series (6a-i) exhibited better antitumor activity than 1-(4-methoxyphenyl) series (6j-p). 4-[2-(4- Fluorobenzylidene)hydrazinyl]-3-(methylsulphanyl)-1-phenyl-1H-pyrazolo[3,4-d] pyrimidine (6d) was the most active compound in this study with IC50 equal to 7.5 nM.