1416767-53-7Relevant articles and documents
Direct imine acylation: Rapid access to diverse heterocyclic scaffolds
Unsworth, William P.,Kitsiou, Christiana,Taylor, Richard J. K.
supporting information, p. 258 - 261 (2013/03/13)
A simple and efficient procedure to prepare a range of diverse heterocycles by the direct acylation of imines using a variety of functionalized benzoic acids is described. The methodology features a novel method for N-acyliminium ion generation followed by in situ intramolecular trapping by oxygen-, nitrogen-, sulfur-and carbon-based nucleophiles. Preliminary mechanistic studies, using ReactIR, are also reported.