141836-47-7

Basic information

• Product Name: Cyclohexanecarboxaldehyde, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-
• CAS NO: 141836-47-7
• Molecular Formula: C14H28O2Si
• Molecular Weight: 256.461
• Mol File: 141836-47-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxaldehyde, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxaldehyde, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-(141836-47-7)
• EPA Substance Registry System: Cyclohexanecarboxaldehyde, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-(141836-47-7)

Safety Data

• Hazardous Substances Data: 141836-47-7(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 13380-84-2 4-(hydroxymethyl)cyclohexane-1-carboxylic acid 
• 105-08-8 bis-1,4-(hydroxymethyl)cyclohexane 
• 141836-50-2 trans-[4-(tert-butyl-dimethyl-silanyloxymethyl)-cyclohexyl]-methanol 

Downstream Products

• 672314-40-8 (R)-N-[(4'-tert-butyldimethylsilyloxymethyl-cyclohexyl)methylidene]-1-phenylethanamine 
• 672314-41-9 (S)-N-[(4'-tert-butyldimethylsilyloxymethyl-cyclohexyl)methylidene]-1-phenylethanamine 
• 672314-42-0 (S)-N-[4'-(tert-butyldimethylsilyloxymethylcyclohexyl)methylidene]-1-amino-2-(methoxymethyl)pyrrolidine 
• 672314-48-6 (R)-N-[4'-(tert-butyldimethylsilyloxymethylcyclohexyl)methylidene]-1-amino-2-(methoxymethyl)pyrrolidine 
• 671815-85-3 N-[4'-(tert-butyldimethylsilyloxymethyl-cyclohexyl)methylidene]benzylamine 
• 129830-38-2 (-)-Y-27632 
• 786659-19-6 {1-[4-(pyridin-4-ylcarbamoyl)-cyclohexyl]-but-3-enyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF

The invention provides compounds for inhibiting glucosylceramidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.

IMIDAZOLE COMPOUND

Disclosed is an imidazole compound, in particular, the compound as shown in formula (I) and a pharmaceutically acceptable salt or tautomer thereof are disclosed.

Synthesis and evaluation of 4-(1-aminoalkyl)-N-(4-pyridyl) cyclohexanecarboxamides as Rho kinase inhibitors and neurite outgrowth promoters

The influence of stereochemistry and alkyl side chain length on the bioactivity of the Rho kinase inhibitor Y-27632 [(+)-1, R = Me] was examined by the synthesis of (+)- and (-)-1, and two alkyl chain analogs (+)- and (-)-2 (R = n-propyl) and (-)-3 (R = n