14185-43-4

Basic information

• Product Name: (R)-(1-phenylethyl)-carbamic acid ethyl ester
• Synonyms: (R)-(1-phenylethyl)-carbamic acid ethyl ester
• CAS NO: 14185-43-4
• Molecular Weight: 193.246
• Mol File: 14185-43-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (R)-(1-phenylethyl)-carbamic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(1-phenylethyl)-carbamic acid ethyl ester(14185-43-4)
• EPA Substance Registry System: (R)-(1-phenylethyl)-carbamic acid ethyl ester(14185-43-4)

Safety Data

• Hazardous Substances Data: 14185-43-4(Hazardous Substances Data)

Upstream product

• 10341-75-0 (E)-1-phenylethanone oxime 
• 541-41-3 chloroformic acid ethyl ester 
• 28570-76-5 (E)-ethanone-1-phenyl-O-(phenylmethyl)oxime 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 

Downstream Products

• 29882-69-7 potassium syn-(R)-1-phenylethanediazoate 
• 163562-74-1 (+)-(R)-N-methyl-N-propargyl-1-phenylethylamine 
• 5933-40-4 (R)-(+)-N,α-dimethylbenzylamine 
• 143678-71-1 (+)-(R)-ethyl N-nitroso-N-(1-phenylethyl)carbamate 
• 33290-10-7 (R)-ONN-1-Phenylazoxyethan 

Relevant articles and documents

Synthesis of limonene β-amino alcohol from (R)-(+)-α-methylbenzylamine and (+)-limonene 1,2-epoxide

Two new compounds of β-amino alcohol are obtained using (R) - (+) - α-methylbenzylamine as starting material which is converted into two amines. Each of these compounds reacted in excess with a 1: 1 mixture of cis and trans-limonene oxide in the presence of water as a catalyst. The products obtained show that β-amino alcohol derived from trans-limonene oxide is obtained and unreacted cis-limonene oxide from the reaction mixture as well as the amine is attained. Whereas the addition of the synthesized carbamate of the same primary amine over the 1: 1 mixture of cis and trans -limonene oxide in the presence of water results in the hydrolysis product and the recovery of unreacted trans-limonene oxide.

Asymmetric synthesis of primary amines via the spiroborate-catalyzed borane reduction of oxime ethers

The enantioselective borane reduction of O-benzyloxime ethers to primary amines was studied under catalytic conditions using the spiroborate esters 5-10 derived from nonracemic 1,2-amino alcohols and ethylene glycol. Effective catalytic conditions were achieved using only 10% of catalyst 5 derived from diphenylvalinol in dioxane at 0°C resulting in complete conversion to the corresponding primary amine in up to 99% ee.

Revision of azoxy assignments in LL-BH872 and elaiomycin based on circular dichroism sutdies on synthetic azoxy compounds.

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