1420-40-2 Usage
Description
DECAMETHONIUM IODIDE, also known as Trimethyl-[10-(trimethylazaniumyl)decyl]azanium diiodide, is a bisalkaloid derivative of a dicarboxylic acid. It is characterized by its ability to act as a reversible cholinesterase inhibitor, which makes it a promising candidate for various applications in the medical field.
Uses
Used in Pharmaceutical Industry:
DECAMETHONIUM IODIDE is used as a reversible cholinesterase inhibitor for its ability to inhibit the activity of cholinesterase enzymes, which play a crucial role in the breakdown of acetylcholine, a neurotransmitter. This inhibition can help in the treatment of conditions related to impaired cholinergic function, such as myasthenia gravis and certain types of glaucoma.
Additionally, due to its cholinergic properties, DECAMETHONIUM IODIDE may also be explored for its potential use in the treatment of other neurological disorders where cholinergic dysfunction is implicated, such as Alzheimer's disease and other cognitive impairments. However, further research and clinical trials are necessary to establish its efficacy and safety in these applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1420-40-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,2 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1420-40:
(6*1)+(5*4)+(4*2)+(3*0)+(2*4)+(1*0)=42
42 % 10 = 2
So 1420-40-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H38N2.2HI/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2
1420-40-2Relevant articles and documents
The Relevance of Size Matching in Self-assembly: Impact on Regio- and Chemoselective Cocrystallizations
Cao, Rong,Daolio, Andrea,Li, Hongfan,Lin, Jing-Xiang,Resnati, Giuseppe,Scilabra, Patrick,Terraneo, Giancarlo
, p. 11701 - 11704 (2020)
Decamethonium diiodide is reported to perform the chemo- and regioselective encapsulation of para-dihalobenzenes through the competitive formation of halogen-bonded cocrystals starting from solutions that also contain ortho and meta isomers. Selective caging in the solid occurs even when an excess ortho or meta isomers, or even a mixture of them, is present in the solution. A prime matching between the size and shape of the dication and the formed dianions plays a key role in enabling the selective self-assembly, as proven by successful encapsulation of halogen-bond donors as weak as 1,4-dichlorobenzene and by the results of cocrystallization trials involving mismatching tectons. Encapsulated para-dihalobenzenes guest molecules can be removed quantitatively by heating the cocrystals under reduced pressure and be recovered as pure materials. The residual decamethonium diiodide can be recycled with no reduction in selectivity.
