142033-88-3

Basic information

• Product Name: (4S,5R)-2-[(S)-ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide
• CAS NO: 142033-88-3
• Molecular Formula: C₁₂H₁₈NO₃PS
• Molecular Weight: 287.315
• Mol File: 142033-88-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 415.049°C at 760 mmHg
• Flash Point: 204.815°C
• Density: 1.305g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: (4S,5R)-2-[(S)-ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-2-[(S)-ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide(142033-88-3)
• EPA Substance Registry System: (4S,5R)-2-[(S)-ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide(142033-88-3)

Safety Data

• Hazardous Substances Data: 142033-88-3(Hazardous Substances Data)

Usage

Description

(4S,5R)-2-[(S)-Ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide is a heterocyclic chemical compound with the molecular formula C13H18NO2PS. It features a phosphorus and nitrogen atom in its ring structure and is characterized by its chirality, having a non-superimposable mirror image and two stereocenters. (4S,5R)-2-[(S)-Ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide is widely utilized in the fields of organic synthesis and medicinal chemistry, where it serves as a valuable reagent and chiral auxiliary. Moreover, it has garnered interest for its potential biological activities, such as antimicrobial and antifungal properties.

Uses

Used in Organic Synthesis:
(4S,5R)-2-[(S)-Ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide is employed as a reagent in organic synthesis, facilitating various chemical reactions and transformations. Its unique structure and chirality make it a versatile tool for creating complex molecules with high selectivity and efficiency.
Used in Medicinal Chemistry:
In the realm of medicinal chemistry, (4S,5R)-2-[(S)-Ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide is used as a chiral auxiliary. This role is crucial for the development of enantiomerically pure drugs, as it helps in controlling the stereochemistry of the synthesized compounds, leading to improved pharmacological properties and reduced side effects.
Used in Pharmaceutical Industry:
(4S,5R)-2-[(S)-Ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structural features and chirality enable the development of novel drugs with enhanced potency, selectivity, and reduced toxicity.
Used in Antimicrobial Applications:
(4S,5R)-2-[(S)-Ethylsulfinyl]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide has been studied for its potential antimicrobial properties. It can be used as an active ingredient in the development of new antimicrobial agents, targeting a wide range of bacteria and helping to combat the growing issue of antibiotic resistance.
Used in Antifungal Applications:
Similarly, this compound has shown promise in its antifungal activities, making it a valuable candidate for the development of new antifungal drugs. These drugs could be used to treat various fungal infections, addressing the increasing need for novel antifungal agents due to the rise of drug-resistant fungal strains.