142061-15-2

Basic information

• Product Name: (4R,5S)-1,5-dimethyl-4-cyclohexyl-2-imidazolidinone
• Synonyms: (4R,5S)-1,5-dimethyl-4-cyclohexyl-2-imidazolidinone
• CAS NO: 142061-15-2
• Molecular Weight: 196.293
• Mol File: 142061-15-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,5S)-1,5-dimethyl-4-cyclohexyl-2-imidazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-1,5-dimethyl-4-cyclohexyl-2-imidazolidinone(142061-15-2)
• EPA Substance Registry System: (4R,5S)-1,5-dimethyl-4-cyclohexyl-2-imidazolidinone(142061-15-2)

Safety Data

• Hazardous Substances Data: 142061-15-2(Hazardous Substances Data)

Upstream product

• 92841-65-1 (4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one 
• 153946-47-5 (4R,5S,2'S)-4-cyclohexyl-1,5-dimethyl-3-(2-methylpent-4-enoyl)imidazolidin-2-one 
• 100-51-6 benzyl alcohol 
• 142061-16-3 (4R,5S)-1,5-dimethyl-4-cyclohexyl-3-propanoylimidazolidin-2-one 
• 136630-07-4 (4R,5S,2'R,3'R)-3-<3-hydroxy-2-methyl-3-(4-nitrophenyl)propanoyl>-1,5-dimethyl-4-phenylimidazolidin-2-one 
• 136630-06-3 (4R,5S,2'R,3'R)-3-<3-hydroxy-2-methyl-3-(4-methoxyphenyl)propanoyl>-1,5-dimethyl-4-phenylimidazolidin-2-one 
• 136630-05-2 (4R,5S,2'R,3'R)-1,5-dimethyl-4-phenyl-3-(3'-hydroxy-2'-methyl-3'-phenylpropanoyl)imidazolidin-2-one 
• 112712-55-7 deux références XF130 et XF154 
• 50-98-6 ephedrine hydrochloride 
• 153946-45-3 (4R,5S,2'S)-4-cyclohexyl-1,5-dimethyl-3-(2-methyl-3-phenylpropanoyl)imidazolidin-2-one 
• 153946-46-4 (4R,5S,2'S)-4-cyclohexyl-1,5-dimethyl-3-(2-methyldecanoyl)imidazolidin-2-one 
• 67-56-1 methanol 
• 142061-17-4 (4R,5S,2'R,3'S)-4-cyclohexyl-3-(3-hydroxy-2-methylbutanoyl)-1,5-dimethylimidazolidin-2-one 
• 142060-61-5 (4R,5S,2'R,3'R)-4-cyclohexyl-3-(3-hydroxy-2-methyl-3-phenylpropanoyl)-1,5-dimethylimidazolidin-2-one 

Downstream Products

• 331283-86-4 (4R,5S)-4-cyclohexyl-1,5-dimethyl-3-(2-propenoyl)-2-imidazolidinone 
• 142061-18-5 (4R,5S,2'R,3'S)-4-cyclohexyl-3-(3-hydroxy-2,4-dimethylpentanoyl)-1,5-dimethylimidazolidin-2-one 
• 142060-60-4 (4R,5S,2'R,3'S)-4-cyclohexyl-3-(3-cyclohexyl-3-hydroxy-2-methylpropanoyl)-1,5-dimethylimidazolidin-2-one 
• 142060-61-5 (4R,5S,2'R,3'R)-4-cyclohexyl-3-(3-hydroxy-2-methyl-3-phenylpropanoyl)-1,5-dimethylimidazolidin-2-one 
• 142061-17-4 (4R,5S,2'R,3'S)-4-cyclohexyl-3-(3-hydroxy-2-methylbutanoyl)-1,5-dimethylimidazolidin-2-one 
• 153946-47-5 (4R,5S,2'S)-4-cyclohexyl-1,5-dimethyl-3-(2-methylpent-4-enoyl)imidazolidin-2-one 
• 153946-46-4 (4R,5S,2'S)-4-cyclohexyl-1,5-dimethyl-3-(2-methyldecanoyl)imidazolidin-2-one 
• 153946-45-3 (4R,5S,2'S)-4-cyclohexyl-1,5-dimethyl-3-(2-methyl-3-phenylpropanoyl)imidazolidin-2-one 
• 215257-47-9 (4S,5R)-5-Cyclohexyl-3,4-dimethyl-2-oxo-imidazolidine-1-carboxylic acid amide 
• 331284-01-6 (4R,5S)-4-cyclohexyl-1,5-dimethyl-3-[(1S,2S,3R,4R)-3-methylbicyclo[2.2.1]hept-5-en-2-ylcarbonyl]-2-imidazolidinone 
• 331283-87-5 (4R,5S)-4-cyclohexyl-1,5-dimethyl-3-[(1S,2S,4S)-bicyclo[2.2.1]hept-5-en-2-ylcarbonyl]-2-imidazolidinone 
• 331283-97-7 (4R,5S)-3-[(2E)-2-butenoyl]-4-cyclohexyl-1,5-dimethyl-2-imidazolidinone 
• 1027286-09-4 (4S,5R)-5-Cyclohexyl-3,4-dimethyl-2-oxo-imidazolidine-1-carboxylic acid ethyl ester 

Relevant articles and documents

Ephedrine-Derived Imidazolidin-2-ones. Broad Utility Chiral Auxiliaries in Asymmetric Synthesis

The scope of the readily available (4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one (4) and its 4-cyclohexyl analogue 6 as practical, efficient chiral auxiliaries has been demonstrated.The enolate chemistry of their N-acyl derivatives exhibits features which recommend their use in asymmetric synthesis.The stereoselective boron-mediated aldol as well as alkylation and acylation results are presented.The steric control benefit derived by conversion of phenyl to cyclohexyl is highlighted. - Key Words: Imidazolidin-2-one, (4R,5S)-1,5-dimethyl-5-phenyl- or cyclohexyl- / (-)-Ephedrine / Stereoselective aldol / alkylation, acylation