142121-48-0

Basic information

• Product Name: BOC-D-LEUCINOL 97
• Synonyms: BOC-D-LEUCINOL 97;Boc-DL-Leucinol;(r)-n-(tert-butoxycarbonyl)leucinol;N-BOC-DL-LEUCINOL;tert-Butyl (1-hydroxy-4-methylpentan-2-yl)carbamate
• CAS NO: 142121-48-0
• Molecular Formula: C₁₁H₂₃NO₃
• Molecular Weight: 217.30522
• Mol File: 142121-48-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 213 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 0.983 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.449(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: BOC-D-LEUCINOL 97(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-D-LEUCINOL 97(142121-48-0)
• EPA Substance Registry System: BOC-D-LEUCINOL 97(142121-48-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 142121-48-0(Hazardous Substances Data)

Usage

General Description

BOC-D-LEUCINOL 97 is a chemical compound that is used in the production of peptide and protein-based pharmaceuticals. It is a derivative of the amino acid leucine, with a tert-butoxycarbonyl (BOC) protective group attached to the amino group. This protective group enables the compound to be used in peptide synthesis, protecting the amino group from unwanted reactions and allowing for selective deprotection during the synthesis process. BOC-D-LEUCINOL 97 is known for its high purity and is commonly used in research and industrial settings for the production of complex peptides and proteins. Its chemical properties make it an essential component in the synthesis of bioactive compounds for various medical and scientific applications.

Upstream product

• 117049-12-4 2-tert-Butoxycarbonylamino-4-methyl-pentanoic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 4530-20-5 BOC-glycine 
• 117681-86-4 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (tert-butoxycarbonyl)aminoacetate 
• 117049-08-8 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl<(tert-butoxycarbonyl)amino>bromoacetate 
• 16369-17-8 2-amino-4-methylpentan-1-ol 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 13139-15-6 Boc-DL-Leu-OH 

Relevant articles and documents

GLYCINE TRANSPORTER-INHIBITING SUBSTANCES

The present invention relates to novel compounds of formula [I] or pharmaceutically acceptable salts thereof: The compounds of the present invention are useful in the prevention or treatment of diseases such as schizophrenia, Alzheimer's disease, cognitive impairment, dementia, anxiety disorders (e.g., generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, post-traumatic stress disorder, specific phobias, acute stress disorder), depression, drug dependence, spasm, tremor, pain, Parkinson's disease, attention deficit hyperactivity disorder, bipolar disorder, eating disorder, or sleep disorders, which is based on the glycine uptake-inhibiting action.

A Mild and Rapid Regeneration of Alcohols from Allyl Ethers by ZrCl4/NaBH4

A new extremely facile, spontaneous and efficient cleavage of allyl protection is developed employing ZrCl4/NaBH4.