1422023-32-2 Usage
Description
Cefoxitin Impurity 6, also known as Δ2-Cefoxitin, is a derivative of Cefoxitin (C243200), which is a semi-synthetic antibiotic derived from Cephamycin C. It is characterized by its high resistance to β-lactamase inactivation, making it a potent antibacterial agent.
Uses
Used in Pharmaceutical Industry:
Cefoxitin Impurity 6 is used as an antibacterial agent for its high resistance to β-lactamase inactivation. This property makes it effective against a wide range of bacterial infections, particularly those caused by β-lactamase-producing bacteria.
Used in Research and Development:
In addition to its clinical applications, Cefoxitin Impurity 6 is also utilized in research and development for studying the mechanisms of bacterial resistance and the development of new antibiotics with improved resistance to β-lactamase inactivation.
Used in Quality Control:
Cefoxitin Impurity 6 is employed in the quality control of Cefoxitin products to ensure their purity and efficacy. By monitoring the presence of this impurity, manufacturers can maintain the quality and safety of the final product.
Check Digit Verification of cas no
The CAS Registry Mumber 1422023-32-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,2,0,2 and 3 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1422023-32:
(9*1)+(8*4)+(7*2)+(6*2)+(5*0)+(4*2)+(3*3)+(2*3)+(1*2)=92
92 % 10 = 2
So 1422023-32-2 is a valid CAS Registry Number.
1422023-32-2Relevant articles and documents
Preparation of three impurities in cefoxitin
Yu, Jun,Jiang, Luo-bing,Feng, Wei-dong,Zhao, Chuan-meng,Zhang, Fu-li
, p. 541 - 546 (2018)
Three known impurities of cefoxitin have been prepared and characterised. One is a double-bond isomer of cefoxitin, ?3-cefoxitin, which was easily prepared by base-catalysed isomerisation of cefoxitin. The second is a side-chain methoxylated derivative, methoxycefoxitin, which required a four-step synthesis from cephalothin. The last impurity is a lactone lacking the carbamyl grouping in cefoxitin, cefoxitin lactone, which was also prepared in four steps from cephalothin. The accessibility of these three impurities and methods for their analysis could be important for quality control in the manufacture of cefoxitin.
